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DC 271

Fluorescent retinoic acid analog; solvochromatic probe

Specification or purity: ≥98%(HPLC)

In stock

DC 271

MSDS

COA

Stock Information

Item (SKU)	Specifications	Is In Stock	Price	Qty
D286991-5mg	5mg	Out of Stock

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Basic Description

Specifications & Purity	≥98%(HPLC)
English Name	DC 271
Synonyms	4-[2-[1,2,3,4-Tetrahydro-4,4-dimethyl-1-(1-methylethyl)-6-quinolinyl]ethynyl]benzoic acid
Biochem Physiol	Fluorescent retinoic acid analog (retinoid all-trans-retinoic acid; ATRA) (Kd= 42 nM at cellular retinoid binding protein II (CRABPII)). Solvochromatic probe: fluorescent λex, λem, and quantum yield affected by solvent type. Activates same genes as endogenous retinoic acid in human keratinocyte cells (HaCaT) when incubated for 72 h at 1 μM. Also elicits cellular responses consistent with those of retinoic acid. Excitation λ = 351, 350, 382 and 378 nm in DMSO, EtOH, DCM and Toluene, respectively; emission λ = 442, 461, 572 and 447 nm in DMSO, EtOH, DCM and Toluene, respectively. Quantum yield = 19.3, 1.14, 71.45, 80.21 % in DMSO, EtOH, DCM and Toluene, respectively
Storage Temp	Store at -20°C
Shipped in	Dry ice

Names and Identifiers

InChi Key	OCMSZODRCJAGHL-UHFFFAOYSA-N
Canonical SMILES	CC(N1CCC(C)(C2=CC(C#CC3=CC=C(C(O)=O)C=C3)=CC=C12)C)C
PubChem CID	22971725
Molecular Weight	347.46

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 17.37, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 3.47, Max Conc. mM: 10

Document Information

Quality Inspection Report COA

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SDS-CN SDS-EN

Specification Sheet

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