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Dihydrofolic acid

Specification or purity: 90%

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Dihydrofolic acid

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COA

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Item (SKU)	Specifications	Is In Stock	Price	Qty
D135507-5mg	5mg	In Stock
D135507-25mg	25mg	In Stock
D135507-50mg	50mg	In Stock
D135507-100mg	100mg	In Stock

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Basic Description

Specifications & Purity	90%
English Name	Dihydrofolic acid
Synonyms	7,8-Dihydropteroyl-L-glutamic acid,Dihydropteroyl-L-glutamic acid,FAH2
synonyms	Dihydrofolic acid\|dihydrofolate\|4033-27-6\|7,8-Dihydrofolic acid\|7,8-Dihydropteroyl-L-glutamic acid\|7,8-dihydrofolate\|7,8-Dihydropteroylglutamate\|7,8-Dihydro-L-folic acid\|CHEBI:15633\|KXP0KNM559\|CHEMBL46294\|(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin
Biochem Physiol	Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
Storage Temp	Protected from light,Store at -20°C
Shipped in	Dry ice
Notes	卖完停产，不再备货
General description	Description Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase. Applications Dihydrofolic Acid is an intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). Folic acid (FA) and Dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF). Description Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase. Applications Dihydrofolic Acid is an intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). Folic acid (FA) and Dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF).

Names and Identifiers

IUPAC Name	(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
INCHI	InChI=1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t12-/m0/s1
InChi Key	OZRNSSUDZOLUSN-LBPRGKRZSA-N
Canonical SMILES	C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
WGK Germany	3
PubChem CID	135398604
Molecular Weight	443.41
Beilstein号	69017

Chemical and Physical Properties

Sensitivity	light 、air、hygroscopic、heat Sensitive

Safe Information

Pictograms	Harmful
Signal word	Warning
Hazard statements	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation
Precautionary statements	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany	3
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves

Document Information

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