91高清自产国产拍,无码免费A级毛片大全,日本欧美国产中文字幕,99re热视频这里只有精品视频首页

400-620-6333

提交您使用阿拉丁产品的研究文章，就得100元奖励！立即访问我们的提交页面.

语言

切换导航

我的购物车

搜索

语言

维兰特罗

规格或纯度: ≥98%

CAS编号: 503068-34-6
分子式: C₂₄H₃₃Cl₂NO₅
分子量: 486.43
PubChem编号: 10184665

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
V126837-5mg	5mg	现货
V126837-25mg	25mg	现货
V126837-50mg	50mg	现货
V126837-500mg	500mg	期货

查看相关系列

β2-adrenoceptor Agonist

Skip to the end of the images gallery

main product photo

Skip to the beginning of the images gallery

基本描述

规格或纯度	≥98%
英文名称	Vilanterol
别名	维兰特罗
英文别名	Vilanterol\|503068-34-6\|GW642444x\|GW-642444x\|UNII-028LZY775B\|CHEBI:75037\|GW642444\|GW-642444\|028LZY775B\|Vilanterol (USAN)\|4-[(1R)-2-[(6-{2-[(2,6-dichlorophenyl)methoxy]ethoxy}hexyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol\|4-[(1R)-2-[6-[2-[(2,6-dichlor
生化机理	in vitro:Vilanterol displayed a subnanomolar affinity for the β(2)-AR that was comparable with that of salmeterol but higher than olodaterol, formoterol, and indacaterol. In cAMP functional activity studies, vilanterol demonstrated similar selectivity as salmeterol for β(2)- over β(1)-AR and β(3)-AR, but a significantly improved selectivity profile than formoterol and indacaterol. Vilanterolalso showed a level of intrinsic efficacy that was comparable to indacaterol but significantly greater than that of salmeterol。 in vivo: The combination of FF/VI at a strength of 100/25 μg significantly (p < 0.001) improved wm FEV1 (173 ml) and troμgh FEV1 (115 ml) vs. placebo. Similar effects were observed with FF/VI 50/25 μg. VI 25 μg over 24 weeks improved lung function vs. placebo significantly for wm FEV1 (103 ml, p < 0.001) and troμgh FEV1 (67 ml, p = 0.017)
储存温度	-20°C储存
运输条件	超低温冰袋运输
备注	5mg、50mg、25mg卖完停产，不再备货
产品介绍	Vilanterol (GW642444; GW 642444X)是吸入型长效β2激动剂。 Vilanterol (GW642444; GW 642444X) is a novel, inhaled, long-acting β(2) agonist with inherent 24-h activity under development as a once-daily combination therapy with an inhaled corticosteroid for COPD and asthma.

名称和标识符

IUPAC Name	4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
INCHI	InChI=1S/C24H33Cl2NO5/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28/h5-9,14,24,27-30H,1-4,10-13,15-17H2/t24-/m0/s1
InChi Key	DAFYYTQWSAWIGS-DEOSSOPVSA-N
Canonical SMILES	C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O)Cl
PubChem CID	10184665
分子量	486.43

数据库链接

ChEMBL Ligand	CHEMBL1198857
PubChem CID	10184665
CAS Registry No.	503068-34-6
Wikipedia	Vilanterol
DrugCentral Ligand	4799
GPCRdb Ligand	vilanterol

化学和物理性质

溶解性	25°C: DMSO

安全和危险性（GHS）

象形图	Health Hazard Environmental Hazard
信号词	Danger
危险声明	H411: Toxic to aquatic life with long lasting effects H370: Causes damage to organs
预防措施声明	P273,P321,P405,P501,P264,P260,P270,P391,P308+P316

关联配体

Ligand ID	7353
名称	vilanterol
别名	GW642444X
类别	Synthetic organic
学名	4-[(1R)-2-[(6-{2-[(2,6-dichlorophenyl)methoxy]ethoxy}hexyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
生物活性评价	The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).
评价	Vilanterol is an ultra-long-acting β2-adrenoreceptor agonist, belonging to a group of drugs termed ultra-LABAs.

相关文档

质检报告COA

请输入批号:

SDS中文版 SDS英文版

质量技术规格说明书

产品问答

产品问答

登录提交问题

您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

上海阿拉丁生化科技股份有限公司

销售条款及条件 ? ? ? ? 隐私政策

? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任

沪公网安备 31012002004058号沪ICP备09093490号-2

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。

危险品化学品经营许可证（带存储）

营业执照(三证合一)