Cas(68-26-8), 视黄醇-阿拉丁试剂, 维生素 A,Retinol,

货号 (SKU)	包装规格	是否现货
V111674-25mg	25mg	现货
V111674-50mg	50mg	现货
V111674-100mg	100mg	现货
V111674-250mg	250mg	现货
V111674-500mg	500mg	现货
V111674-1g	1g	现货
V111674-5g	5g	现货

基本描述

规格或纯度	95%
英文名称	Retinol
别名	全反式-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯-1-基)-2,4,6,8-壬四烯-1-醇；抗干眼醇；维生素 A 醇；维生素 A1
英文别名	Axerophthol； Vitamin A alcohol；Vitamin A；Vitamin A1；all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
生化机理	维甲酸受体配体。维甲酸，维生素A的衍生物。调节细胞中的基因转录。棒通道抑制剂（IC 50 = 0.99μM）。
储存温度	-20°C储存,充氩
运输条件	超低温冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	视黄醇或维生素A醇是维生素A的主要循环形式。它不具有生物活性并可作为活性类视黄醇的一种前体。视黄醇可转化为视黄醛，然后再转化为视黄酸。All-trans及9-cis-视黄酸是核受体、视黄酸受体（RAR）和类视黄醇X受体（RXR）的配体。这些受体是多种基因的转录调控因子。视黄酸受体（the retinoic acid receptor，RAR) 和类视黄醇受体（the retinoid X receptor，RXR)的配体，作为其转导因子，调控正常和恶性细胞的生长和分化。 Retinol or vitamin A alcohol is the main circulating form of vitamin A. It is not biologically active. Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (in trans configuration), and an alcohol end group.

名称和标识符

EC号	200-683-7
IUPAC Name	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
INCHI	InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChi Key	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
Canonical SMILES	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C
分子式	C₂₀H₃₀O
PubChem CID	445354
Beilstein号	403040
分子量	286.45

数据库链接

DrugBank Ligand	DB00162
ChEBI	CHEBI:17336
Wikipedia	Retinol
CAS Registry No.	68-26-8
PubChem CID	445354
ChEMBL Ligand	CHEMBL986
RCSB PDB Ligand	RTL
PEP	retinol
DrugCentral Ligand	2831

化学和物理性质

溶解性	Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol, chloroform, ether, fats and oils.
密度	0.954
敏感性	对光及湿度敏感;对空气敏感;
沸点	120-125°C
熔点	61-63°C
折光率	1.641

安全信息

象形图	Health Hazard Harmful
信号词	Danger
危险声明	H319: Causes serious eye irritation H413: May cause long lasting harmful effects to aquatic life H302: Harmful if swallowed H317: May cause an allergic skin reaction H360: May damage fertility or the unborn child
预防措施声明	P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P270,P272,P333+P313,P362+P364,P330,P203,P264+P265,P301+P317,P318,P337+P317
WGK Germany	3
RTECS	VH6750000
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

靶标

Target ID

614

名称

Testicular receptor 4

缩写名

SHP2

家族

2C. Testicular receptors

别名

DCCR2

基因和蛋白信息

Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Human	2	596	3p25.1	NR2C2	nuclear receptor subfamily 2 group C member 2
Mouse	2	596	6 D1	Nr2c2	nuclear receptor subfamily 2, group C, member 2
Rat	2	596	4q34	Nr2c2	nuclear receptor subfamily 2, group C, member 2

Entrez Gene

7182 (Hs) , 50659 (Rn) , 22026 (Mm)

OMIM

601426 (Hs)

UniProtKB

P49116 (Hs) , P55094 (Rn) , P49117 (Mm)

RefSeq Nucleotide

NM_003298 (Hs) , NM_017323 (Rn) , NM_011630 (Mm)

RefSeq Protein

NP_003289 (Hs) , NP_035760 (Mm) , NP_059019 (Rn)

Ensembl Gene

ENSG00000177463 (Hs) , ENSMUSG00000005893 (Mm) , ENSRNOG00000010536 (Rn)

Protein GI

8394483 (Rn) , 36950991 (Hs) , 67906168 (Mm)

NURSA Receptor

10.1621/43Q9BVKDG8 (Hs)

CATH/Gene3D

3.30.50.10 (N/A)

ChEMBL Target

CHEMBL4295769 (Mm) , CHEMBL5716 (Hs)

关联配体

Ligand ID	4053
名称	retinol
别名	all-trans-retinol
类别	Metabolite
学名	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraen-1-ol
生物活性评价	The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).
评价	Retinol (vitamin A₁) plays an essential role in (night) vision, normal bone and tooth development, reproduction, and is required for maintaining the integrity of skin and mucous membranes. It has antioxidant activity.

参考文献

1. Ortu?o MJ et al.. (2021) Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure.. J Clin Invest, 131 (24): (). [PMID:34673574]
2. C L?ser,U R F?lsch,C Paprotny,W Creutzfeldt. (1990-03-01) Polyamine concentrations in pancreatic tissue, serum, and urine of patients with pancreatic cancer.. Pancreas, 5 ((2)): (119-127). [PMID:2315288]
3. T Sakai,K Yamamoto,H Yokota,K Hakozaki-Usui,F Hino,I Kato. (1990-03-01) Rapid, simple enzymatic assay of free L-fucose in serum and urine, and its use as a marker for cancer, cirrhosis, and gastric ulcers.. Clinical chemistry, 36 ((3)): (474-476). [PMID:2311216]
4. G M Pollack,J F Buchanan,R L Slaughter,R K Kohli,D D Shen. (1985-06-30) Circulating concentrations of di(2-ethylhexyl) phthalate and its de-esterified phthalic acid products following plasticizer exposure in patients receiving hemodialysis.. Toxicology and applied pharmacology, 79 ((2)): (257-267). [PMID:4002227]
5. Wellemans V, Laurent S, Hélie P, ElAzhary Y,. () Immunostimulatory properties of a novel adjuvant administered with inactivated influenza virus vaccine.. Vet Res, (): (). [PMID:17074291]
6. D S Gill,V A Fonseca,M A Barradas,R Balliod,J F Moorhead,P Dandona. (1991-03-01) Plasma histamine in patients with chronic renal failure and nephrotic syndrome.. Journal of clinical pathology, 44 ((3)): (243-245). [PMID:2013627]
7. D S Raj,M Ouwendyk,R Francoeur,A Pierratos. (2000-06-06) Plasma amino acid profile on nocturnal hemodialysis.. Blood purification, 18 ((2)): (97-102). [PMID:10838467]
8. R De Smet,J Van Kaer,H Liebich,G Lesaffer,A Verstraete,A Dhondt,P Duym,N Lameire,R Vanholder. (2001-04-28) Heparin-induced release of protein-bound solutes during hemodialysis is an in vitro artifact.. Clinical chemistry, 47 ((5)): (901-909). [PMID:11325895]
9. D O McGregor,W J Dellow,M Lever,P M George,R A Robson,S T Chambers. (2001-05-31) Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.. Kidney international, 59 ((6)): (2267-2272). [PMID:11380830]
10. S C Hung,S H Hung,D C Tarng,W C Yang,T W Chen,T P Huang. (2001-10-31) Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients.. American journal of kidney diseases : the official journal of the National Kidney Foundation, 38 ((5)): (941-947). [PMID:11684545]
11. Lindsay H Allen,Marjorie Haskell. (2002-09-11) Estimating the potential for vitamin A toxicity in women and young children.. The Journal of nutrition, 132 ((9 Suppl)): (2907S-2919S). [PMID:12221269]
12. Frank T Wieringa,Marjoleine A Dijkhuizen,Clive E West,David I Thurnham,Muhilal,Jos W M Van der Meer. (2003-02-26) Redistribution of vitamin A after iron supplementation in Indonesian infants.. The American journal of clinical nutrition, 77 ((3)): (651-657). [PMID:12600856]
13. Joachim Jankowski,Vera Jankowski,Udo Laufer,Markus van der Giet,Lars Henning,Martin Tepel,Walter Zidek,Hartmut Schlüter. (2003-05-10) Identification and quantification of diadenosine polyphosphate concentrations in human plasma.. Arteriosclerosis, thrombosis, and vascular biology, 23 ((7)): (1231-1238). [PMID:12738682]
14. A Catharine Ross. (2004-01-09) On the sources of retinoic acid in the lung: understanding the local conversion of retinol to retinoic acid.. American journal of physiology. Lung cellular and molecular physiology, 286 ((2)): (L247-L248). [PMID:14711799]
15. Grace M Egeland,Peter Berti,Rula Soueida,Laura T Arbour,Olivier Receveur,Harriet V Kuhnlein. (2004-12-30) Age differences in vitamin A intake among Canadian Inuit.. Canadian journal of public health = Revue canadienne de sante publique, 95 ((6)): (465-469). [PMID:15622799]
16. Poliana Coelho Cabral,Alcides da Silva Diniz,Ilma Kruze Grande de Arruda. (2005-10-14) Vitamin A and zinc status in patients on maintenance haemodialysis.. Nephrology (Carlton, Vic.), 10 ((5)): (459-463). [PMID:16221095]
17. Martin Lidén,Ulf Eriksson. (2006-01-24) Understanding retinol metabolism: structure and function of retinol dehydrogenases.. The Journal of biological chemistry, 281 ((19)): (13001-13004). [PMID:16428379]
18. C Redondo,B J Burke,J B C Findlay. (2006-05-16) The retinol-binding protein system: a potential paradigm for steroid-binding globulins?. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 38 ((4)): (269-278). [PMID:16700009]
19. Masahiko Yano,Masanori Ikeda,Ken-Ichi Abe,Hiromichi Dansako,Shogo Ohkoshi,Yutaka Aoyagi,Nobuyuki Kato. (2007-04-11) Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture.. Antimicrobial agents and chemotherapy, 51 ((6)): (2016-2027). [PMID:17420205]
20. George Wolf. (2007-09-18) Identification of a membrane receptor for retinol-binding protein functioning in the cellular uptake of retinol.. Nutrition reviews, 65 ((8 Pt 1)): (385-388). [PMID:17867372]
21. Roxana A Radu,Jane Hu,Jennifer Peng,Dean Bok,Nathan L Mata,Gabriel H Travis. (2008-05-14) Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells.. The Journal of biological chemistry, 283 ((28)): (19730-19738). [PMID:18474598]
22. Stephen J Williams,Dusica Cvetkovic,Thomas C Hamilton. (2008-12-27) Vitamin A metabolism is impaired in human ovarian cancer.. Gynecologic oncology, 112 ((3)): (637-645). [PMID:19110304]
23. George Magoulas,Dionysios Papaioannou,Evangelia Papadimou,Denis Drainas. (2009-02-14) Preparation of spermine conjugates with acidic retinoids with potent ribonuclease P inhibitory activity.. European journal of medicinal chemistry, 44 ((6)): (2689-2695). [PMID:19216007]
24. Nathan Bushue,Yu-Jui Yvonne Wan. (2010-07-27) Retinoid pathway and cancer therapeutics.. Advanced drug delivery reviews, 62 ((13)): (1285-1298). [PMID:20654663]
25. Hui Sun,Riki Kawaguchi. (2011-04-13) The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor.. International review of cell and molecular biology, 288 (): (1-41). [PMID:21482409]
26. David Planer,Shulamit Metzger,Eyal Zcharia,Isaiah D Wexler,Israel Vlodavsky,Tova Chajek-Shaul. (2011-04-13) Role of heparanase on hepatic uptake of intestinal derived lipoprotein and fatty streak formation in mice.. PloS one, 6 ((4)): (e18370-e18370). [PMID:21483695]
27. J Valtue?a,C Breidenassel,J Folle,M González-Gross. (2011-06-15) Retinol, β-carotene, α-tocopherol and vitamin D status in European adolescents; regional differences an variability: a review.. Nutricion hospitalaria, 26 ((2)): (280-288). [PMID:21666963]
28. Amanda C Palmer,Keith P West,Nita Dalmiya,Werner Schultink. (2012-03-10) The use and interpretation of serum retinol distributions in evaluating the public health impact of vitamin A programmes.. Public health nutrition, 15 ((7)): (1201-1215). [PMID:22401130]
29. Ming Zhong,Riki Kawaguchi,Miki Kassai,Hui Sun. (2013-02-01) Retina, retinol, retinal and the natural history of vitamin A as a light sensor.. Nutrients, 4 ((12)): (2069-2096). [PMID:23363998]
30. Jiaoyang Cao,Xiaoping Wei,Xianqiang Tang,Hongpeng Jiang,Zhen Fan,Qin Yu,Jie Chen,Youxue Liu,Tingyu Li. (2013-05-03) Effects of egg and vitamin A supplementation on hemoglobin, retinol status and physical growth levels of primary and middle school students in Chongqing, China.. Asia Pacific journal of clinical nutrition, 22 ((2)): (214-221). [PMID:23635364]
31. Maria E Sundaram,Alain B Labrique,Sucheta Mehra,Hasmot Ali,Abu A Shamim,Rolf D W Klemm,Keith P West,Parul Christian. (2013-05-17) Early neonatal feeding is common and associated with subsequent breastfeeding behavior in rural Bangladesh.. The Journal of nutrition, 143 ((7)): (1161-1167). [PMID:23677862]
32. Emily K Heying,Michael Grahn,Kevin V Pixley,Torbert Rocheford,Sherry A Tanumihardjo. (2013-05-31) High-provitamin A carotenoid (Orange) maize increases hepatic vitamin A reserves of offspring in a vitamin A-depleted sow-piglet model during lactation.. The Journal of nutrition, 143 ((7)): (1141-1146). [PMID:23719225]
33. Peter Patlevic,Janka Vasková,Ladislav Vasko,Darina Kluchová. (2013-07-04) Postnatal development of spinal cord and liver antioxidant status in the young of retinol-overdosed female rats.. Zeitschrift fur Naturforschung. C, Journal of biosciences, 68 ((3-4)): (155-163). [PMID:23819312]
34. Samson Gebremedhin Gebreselassie,Fikre Enquselassie Gase,Melaku Umeta Deressa. (2013-08-13) Prevalence and correlates of prenatal vitamin A deficiency in rural Sidama, Southern Ethiopia.. Journal of health, population, and nutrition, 31 ((2)): (185-194). [PMID:23930336]
35. Joe Swift,Irena L Ivanovska,Amnon Buxboim,Takamasa Harada,P C Dave P Dingal,Joel Pinter,J David Pajerowski,Kyle R Spinler,Jae-Won Shin,Manorama Tewari,Florian Rehfeldt,David W Speicher,Dennis E Discher. (2013-08-31) Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.. Science (New York, N.Y.), 341 ((6149)): (1240104-1240104). [PMID:23990565]
36. Nipa Rojroongwasinkul,Kallaya Kijboonchoo,Wanphen Wimonpeerapattana,Sasiumphai Purttiponthanee,Uruwan Yamborisut,Atitada Boonpraderm,Petcharat Kunapan,Wiyada Thasanasuwan,Ilse Khouw. (2013-09-18) SEANUTS: the nutritional status and dietary intakes of 0.5-12-year-old Thai children.. The British journal of nutrition, 110 Suppl 3 (): (S36-S44). [PMID:24016765]
37. Gurdeep Marwarha,Daniel C Berry,Colleen M Croniger,Noa Noy. (2013-09-17) The retinol esterifying enzyme LRAT supports cell signaling by retinol-binding protein and its receptor STRA6.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28 ((1)): (26-34). [PMID:24036882]
38. Bruce Alberts,Roger Beachy,David Baulcombe,Gunter Blobel,Swapan Datta,Nina Fedoroff,Donald Kennedy,Gurdev S Khush,Jim Peacock,Martin Rees,Phillip Sharp. (2013-09-21) Standing up for GMOs.. Science (New York, N.Y.), 341 ((6152)): (1320-1320). [PMID:24052276]
39. R Yasmeen,J M Meyers,C E Alvarez,J L Thomas,A Bonnegarde-Bernard,H Alder,T L Papenfuss,D M Benson,P N Boyaka,O Ziouzenkova. (2013-10-02) Aldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations.. Biochimica et biophysica acta, 1833 ((12)): (3218-3227). [PMID:24080087]
40. Jaume Amengual,M Airanthi K Widjaja-Adhi,Susana Rodriguez-Santiago,Susanne Hessel,Marcin Golczak,Krzysztof Palczewski,Johannes von Lintig. (2013-10-10) Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.. The Journal of biological chemistry, 288 ((47)): (34081-34096). [PMID:24106281]
41. Sherry A Tanumihardjo. (2013-11-05) Vitamin A and bone health: the balancing act.. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 16 ((4)): (414-419). [PMID:24183637]
42. Mohamed Mohammed El-Sayed,Doaa Ahmad Ghareeb,Heba Allah Talat,Eman Mohammed Sarhan. (2013-11-06) High fat diet induced insulin resistance and elevated retinol binding protein 4 in female rats; treatment and protection with Berberis vulgaris extract and vitamin A.. Pakistan journal of pharmaceutical sciences, 26 ((6)): (1189-1195). [PMID:24191325]
43. Adrienne McMahon,Scott Christiansen,Lynsey Shine,Calvin Loi,Dawn Dowell. (2013-11-29) Simultaneous determination of 13-cis and all-trans vitamin A palmitate (retinyl palmitate), vitamin A acetate (retinyl acetate), and total vitamin E (alpha-tocopherol and DL-alpha-tocopherol acetate) in infant formula and adult nutritionals by normal phase HPLC: first action 2012.10.. Journal of AOAC International, 96 ((5)): (1073-1081). [PMID:24282950]
44. Diego Moretti,Ralf Biebinger,Maaike J Bruins,Birgit Hoeft,Klaus Kraemer. (2013-12-18) Bioavailability of iron, zinc, folic acid, and vitamin A from fortified maize.. Annals of the New York Academy of Sciences, 1312 (): (54-65). [PMID:24329552]
45. Reina Engle-Stone,Marjorie J Haskell,Martin Nankap,Alex O Ndjebayi,Kenneth H Brown. (2013-12-18) Breast milk retinol and plasma retinol-binding protein concentrations provide similar estimates of vitamin A deficiency prevalence and identify similar risk groups among women in Cameroon but breast milk retinol underestimates the prevalence of deficiency among young children.. The Journal of nutrition, 144 ((2)): (209-217). [PMID:24336458]
46. Rajeev Rudraraju,Bart G Jones,Sherri L Surman,Robert E Sealy,Paul G Thomas,Julia L Hurwitz. (2014-01-28) Respiratory tract epithelial cells express retinaldehyde dehydrogenase ALDH1A and enhance IgA production by stimulated B cells in the presence of vitamin A.. PloS one, 9 ((1)): (e86554-e86554). [PMID:24466150]
47. Kathryn A Thornton,Mercedes Mora-Plazas,Constanza Marín,Eduardo Villamor. (2014-02-07) Vitamin A deficiency is associated with gastrointestinal and respiratory morbidity in school-age children.. The Journal of nutrition, 144 ((4)): (496-503). [PMID:24500929]
48. Siwaporn Pinkaew,Rita Wegmuller,Emorn Wasantwisut,Pattanee Winichagoon,Richard F Hurrell,Sherry A Tanumihardjo. (2014-02-07) Triple-fortified rice containing vitamin A reduced marginal vitamin A deficiency and increased vitamin A liver stores in school-aged Thai children.. The Journal of nutrition, 144 ((4)): (519-524). [PMID:24500930]
49. Lin Chen,Xinke Chen,Qin Xiang,Yuqiang Zheng,Lianhong Pi,Qin Liu,Jun Xiao,Ning Ke,Jing Fang. (2014-02-12) Prevalence of low serum vitamin a levels in young children with chalazia in southwest china.. American journal of ophthalmology, 157 ((5)): (1103-1108). [PMID:24513096]
50. Maha Ben Mustapha,Mehrez Bousselmi,Ta?eb Jerbi,Nasreddine Ben Betta?eb,Sami Fattouch. (2014-02-13) Gamma radiation effects on microbiological, physico-chemical and antioxidant properties of Tunisian millet (Pennisetum Glaucum L.R.Br.).. Food chemistry, 154 (): (230-237). [PMID:24518337]
51. Brunhild M Halm,Jennifer F Lai,Cynthia M Morrison,Ian Pagano,Laurie J Custer,Robert V Cooney,Adrian A Franke. (2014-03-04) In vivo changes in plasma coenzyme Q10, carotenoid, tocopherol, and retinol levels in children after computer tomography.. Archives of biochemistry and biophysics, 547 (): (37-43). [PMID:24583267]
52. Kara A Bresnahan,Christopher R Davis,Sherry A Tanumihardjo. (2014-04-09) Relative vitamin A values of 9-cis- and 13-cis-β-carotene do not differ when fed at physiological levels during vitamin A depletion in Mongolian gerbils (Meriones unguiculatus).. The British journal of nutrition, 112 ((2)): (162-169). [PMID:24709067]
53. Shaher Samrah,Ibrahim Khatib,Muntaser Omari,Basheer Khassawneh,Suleiman Momany,Ammar Daoud,Musa Malkawi,Yousef Khader. (2014-05-02) Vitamin D deficiency and level of asthma control in women from North of Jordan: a case-control study.. The Journal of asthma : official journal of the Association for the Care of Asthma, 51 ((8)): (832-838). [PMID:24779968]
54. Ana Freitas,Margarida Mold?o-Martins,Helena S Costa,Tania G Albuquerque,Ana Valente,Ana Sanches-Silva. (2014-05-24) Effect of UV-C radiation on bioactive compounds of pineapple (Ananas comosus L. Merr.) by-products.. Journal of the science of food and agriculture, 95 ((1)): (44-52). [PMID:24852602]
55. Napaporn Riabroy,Sherry A Tanumihardjo. (2014-06-20) Oral doses of α-retinyl ester track chylomicron uptake and distribution of vitamin A in a male piglet model for newborn infants.. The Journal of nutrition, 144 ((8)): (1188-1195). [PMID:24944285]
56. Farzana Ferdous,Sumon Kumar Das,Shahnawaz Ahmed,Fahmida Dil Farzana,Mohammad Abdul Malek,Jui Das,Jonathan Ross Latham,Abu Syed Golam Faruque,Mohammod Jobayer Chisti. (2014-07-22) Diarrhoea in slum children: observation from a large diarrhoeal disease hospital in Dhaka, Bangladesh.. Tropical medicine & international health : TM & IH, 19 ((10)): (1170-1176). [PMID:25039966]
57. Indumathi Manoharan,Yuan Hong,Amol Suryawanshi,Melinda L Angus-Hill,Zuoming Sun,Andrew L Mellor,David H Munn,Santhakumar Manicassamy. (2014-09-12) TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation.. Journal of immunology (Baltimore, Md. : 1950), 193 ((8)): (4203-4213). [PMID:25210120]
58. Ilona Ol?dzka,Katarzyna Ka?mierska,Alina Plenis,Barbara Kamińska,Tomasz B?czek. (2014-09-23) Capillary electromigration techniques as tools for assessing the status of vitamins A, C and E in patients with cystic fibrosis.. Journal of pharmaceutical and biomedical analysis, 102 (): (45-53). [PMID:25240158]
59. Hannah E Smith,Kelsey N Ryan,Kevin B Stephenson,Claire Westcott,Chrissie Thakwalakwa,Ken Maleta,Jacqueline Y Cheng,J Thomas Brenna,Robert J Shulman,Indi Trehan,Mark J Manary. (2014-11-21) Multiple micronutrient supplementation transiently ameliorates environmental enteropathy in Malawian children aged 12-35 months in a randomized controlled clinical trial.. The Journal of nutrition, 144 ((12)): (2059-2065). [PMID:25411039]
60. Samridhi Sharma,Sandipan Ray,Shuvolina Mukherjee,Aliasgar Moiyadi,Epari Sridhar,Sanjeeva Srivastava. (2014-11-22) Multipronged quantitative proteomic analyses indicate modulation of various signal transduction pathways in human meningiomas.. Proteomics, 15 ((2-3)): (394-407). [PMID:25413884]
61. Ibironke O Olofin,Donna Spiegelman,Said Aboud,Christopher Duggan,Goodarz Danaei,Wafaie W Fawzi. (2014-12-02) Supplementation with multivitamins and vitamin A and incidence of malaria among HIV-infected Tanzanian women.. Journal of acquired immune deficiency syndromes (1999), 67 Suppl 4 (): (S173-S178). [PMID:25436815]
62. Kathleen E Sullivan,Greg Fleming,Scott Terrell,Dustin Smith,Frank Ridgley,Eduardo V Valdes. (2015-01-31) Vitamin A values of wild-caught Cuban tree frogs (Osteopilus septentrionalis) and marine toads (Rhinella marina) in whole body, liver, and serum.. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 45 ((4)): (892-895). [PMID:25632678]
63. Arnaud Laillou,Cécile Renaud,Jacques Berger,Regina Moench-Pfanner,Laura Fontan,Sylvie Avallone. (2015-02-03) Assessment of a portable device to quantify vitamin A in fortified foods (flour, sugar, and milk) for quality control.. Food and nutrition bulletin, 35 ((4)): (449-457). [PMID:25639130]
64. Liheng Shi,Soyoung Ko,Michael L Ko,Andy Jeesu Kim,Gladys Y-P Ko. (2015-02-24) Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling.. Biochimica et biophysica acta, 1853 ((5)): (1154-1164). [PMID:25698653]
65. Jeanine M Genkinger,Laura Stigter,Wieslaw Jedrychowski,Tzu-Jung Huang,Shuang Wang,Emily L Roen,Renata Majewska,Agnieszka Kieltyka,Elzbieta Mroz,Frederica P Perera. (2015-04-12) Prenatal polycyclic aromatic hydrocarbon (PAH) exposure, antioxidant levels and behavioral development of children ages 6-9.. Environmental research, 140 (): (136-144). [PMID:25863187]
66. Benito Campos,Sarah Weisang,Florian Osswald,Ramadan Ali,Georg Sedlmeier,Josephine Bageritz,Jan-Philipp Mallm,Christian Hartmann,Andreas von Deimling,Odillia Popanda,Violaine Goidts,Christoph Plass,Andreas Unterberg,Peter Schmezer,Jürgen Burhenne,Christel Herold-Mende. (2015-05-07) Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma.. Glia, 63 ((10)): (1850-1859). [PMID:25944104]
67. Mohammad Nurul Amin,Kaniz Fatema Liza,Md Shahid Sarwar,Jamiuddin Ahmed,Md Tareek Adnan,Manjurul Islam Chowdhury,Mohammad Zahid Hossain,Mohammad Safiqul Islam. (2015-05-15) Effect of lipid peroxidation, antioxidants, macro minerals and trace elements on eczema.. Archives of dermatological research, 307 ((7)): (617-623). [PMID:25967637]
68. Rupsa Datta,Alba Alfonso-García,Rachel Cinco,Enrico Gratton. (2015-05-21) Fluorescence lifetime imaging of endogenous biomarker of oxidative stress.. Scientific reports, 5 (): (9848-9848). [PMID:25993434]
69. Jailane de Souza Aquino,Juliana Késsia Barbosa Soares,Marciane Magnani,Thayza Christina Montenegro Stamford,Robson de Jesus Mascarenhas,Renata Leite Tavares,Tania Lúcia Montenegro Stamford. (2015-05-23) Effects of Dietary Brazilian Palm Oil (Mauritia flexuosa L.) on Cholesterol Profile and Vitamin A and E Status of Rats.. Molecules (Basel, Switzerland), 20 ((5)): (9054-9070). [PMID:25996211]
70. Ramon A C van Huet,Laurence H M Pierrache,Magda A Meester-Smoor,Caroline C W Klaver,L Ingeborgh van den Born,Carel B Hoyng,Ilse J de Wijs,Rob W J Collin,Lies H Hoefsloot,B Jeroen Klevering. (2015-05-23) The efficacy of microarray screening for autosomal recessive retinitis pigmentosa in routine clinical practice.. Molecular vision, 21 (): (461-476). [PMID:25999674]
71. Mei Du,Laura Otalora,Ashley A Martin,Gennadiy Moiseyev,Phillip Vanlandingham,Qilong Wang,Rafal Farjo,Alexander Yeganeh,Alexander Quiambao,Krysten M Farjo. (2015-06-10) Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism.. Molecular and cellular biology, 35 ((16)): (2771-2789). [PMID:26055327]
72. Daniela Lima,L Filipe C Castro,Inês Coelho,Ricardo Lacerda,Manuel Gesto,Joana Soares,Ana André,Ricardo Capela,Tiago Torres,António Paulo Carvalho,Miguel M Santos. (2015-06-20) Effects of Tributyltin and Other Retinoid Receptor Agonists in Reproductive-Related Endpoints in the Zebrafish (Danio rerio).. Journal of toxicology and environmental health. Part A, 78 ((12)): (747-760). [PMID:26090559]
73. J M Gillbro,M Lundahl,M Westman,R Baral,T Al-Bader,A Mavon. (2015-07-04) Structural activity relationship analysis (SAR) and in vitro testing reveal the anti-ageing potential activity of acetyl aspartic acid.. International journal of cosmetic science, 37 Suppl 1 (): (15-20). [PMID:26139465]
74. Eric M Brown,Marta Wlodarska,Benjamin P Willing,Pascale Vonaesch,Jun Han,Lisa A Reynolds,Marie-Claire Arrieta,Marco Uhrig,Roland Scholz,Oswaldo Partida,Christoph H Borchers,Philippe J Sansonetti,B Brett Finlay. (2015-08-05) Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model.. Nature communications, 6 (): (7806-7806). [PMID:26241678]
75. Yichao Huang,Peter Roy Clements,Robert Alan Gibson. (2015-10-23) Robust measurement of vitamin A status in plasma and blood dried on paper.. Prostaglandins, leukotrienes, and essential fatty acids, 102-103 (): (31-36). [PMID:26489594]
76. Lucie Aumailley,Marie Julie Dubois,Chantal Garand,André Marette,Michel Lebel. (2015-11-03) Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.. Experimental gerontology, 72 (): (192-203). [PMID:26521679]
77. Rebecca King,Lu Lu,Robert W Williams,Eldon E Geisert. (2015-11-26) Transcriptome networks in the mouse retina: An exon level BXD RI database.. Molecular vision, 21 (): (1235-1251). [PMID:26604663]
78. Yuanchao Li,Qin Zhang,Dandan Qi,Li Zhang,Lian Yi,Qianqian Li,Zhongling Zhang. (2016-05-07) Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB.. The journal of headache and pain, 17 (): (49-49). [PMID:27150105]
79. Magdalini Rovoli,Ioannis Pappas,Stavros Lalas,Olga Gortzi,George Kontopidis. (2018-09-07) In vitro and in vivo assessment of vitamin A encapsulation in a liposome-protein delivery system.. Journal of liposome research, 29 ((2)): (142-152). [PMID:30187807]
80. Ala Morshedian,Joanna J Kaylor,Sze Yin Ng,Avian Tsan,Rikard Frederiksen,Tongzhou Xu,Lily Yuan,Alapakkam P Sampath,Roxana A Radu,Gordon L Fain,Gabriel H Travis. (2019-05-06) Light-Driven Regeneration of Cone Visual Pigments through a Mechanism Involving RGR Opsin in Müller Glial Cells.. Neuron, 102 ((6)): (1172-1183). [PMID:31056353]
81. Huili Sun,Xing Guo,Si Zeng,Yi Wang,Jianwen Hou,Donghua Yang,Shaobing Zhou. (2019-09-26) A multifunctional liposomal nanoplatform co-delivering hydrophobic and hydrophilic doxorubicin for complete eradication of xenografted tumors.. Nanoscale, 11 ((38)): (17759-17772). [PMID:31552975]
82. Zili Zhang,Mei Guo,Yujia Li,Min Shen,Desong Kong,Jiangjuan Shao,Hai Ding,Shanzhong Tan,Anping Chen,Feng Zhang,Shizhong Zheng. (2019-11-05) RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells.. Autophagy, 16 ((8)): (1482-1505). [PMID:31679460]
83. Federica Cheli,Ioannis Politis,Luciana Rossi,Eleonora Fusi,Antonella Baldi. (2003-12-03) Effects of retinoids on proliferation and plasminogen activator expression in a bovine mammary epithelial cell line.. The Journal of dairy research, 70 ((4)): (367-372). [PMID:14649406]
84. A Catharine Ross,Reza Zolfaghari. (2004-01-06) Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status.. The Journal of nutrition, 134 ((1)): (269S-275S). [PMID:14704332]
85. David Alberts,James Ranger-Moore,Janine Einspahr,Kathylynn Saboda,Paul Bozzo,Yun Liu,Xiao-Chun Xu,Reuben Lotan,James Warneke,Stuart Salasche,Suzanne Stratton,Norman Levine,Rayna Goldman,Marcy Islas,Laura Duckett,Deborah Thompson,Peter Bartels,Janet Foote. (2004-03-26) Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin.. Clinical cancer research : an official journal of the American Association for Cancer Research, 10 ((6)): (1875-1880). [PMID:15041701]
86. Fernando Granado-Lorencio,Carmer Herrero-Barbudo,Bego?a Olmedilla-Alonso,Inmaculada Blanco-Navarro,Belén Pérez-Sacristán. (2009-02-10) Lutein bioavailability from lutein ester-fortified fermented milk: in vivo and in vitro study.. The Journal of nutritional biochemistry, 21 ((2)): (133-139). [PMID:19201183]
87. Alison M Mondul,Kai Yu,William Wheeler,Hong Zhang,Stephanie J Weinstein,Jacqueline M Major,Marilyn C Cornelis,Satu M?nnist?,Aditi Hazra,Ann W Hsing,Kevin B Jacobs,Heather Eliassen,Toshiko Tanaka,Douglas J Reding,Sara Hendrickson,Luigi Ferrucci,Jarmo Virtamo,David J Hunter,Stephen J Chanock,Peter Kraft,Demetrius Albanes. (2011-09-01) Genome-wide association study of circulating retinol levels.. Human molecular genetics, 20 ((23)): (4724-4731). [PMID:21878437]
88. Masheika L James,A Catharine Ross,Teodora Nicola,Chad Steele,Namasivayam Ambalavanan. (2013-04-16) VARA attenuates hyperoxia-induced impaired alveolar development and lung function in newborn mice.. American journal of physiology. Lung cellular and molecular physiology, 304 ((11)): (L803-L812). [PMID:23585226]
89. Ben Shneiderman. (2014-02-18) The big picture for big data: visualization.. Science (New York, N.Y.), 343 ((6172)): (730-730). [PMID:24531954]
90. Malay Rana,Denise Wong-See,Tamarah Katz,Kevin Gaskin,Bruce Whitehead,Adam Jaffe,John Coakley,Alistair Lochhead. (2014-04-09) Fat-soluble vitamin deficiency in children and adolescents with cystic fibrosis.. Journal of clinical pathology, 67 ((7)): (605-608). [PMID:24711511]
91. Bryan Y Kim,Kamran M Riaz,Pejman Bakhtiari,Clara C Chan,Jeffrey D Welder,Edward J Holland,Surendra Basti,Ali R Djalilian. (2014-06-09) Medically reversible limbal stem cell disease: clinical features and management strategies.. Ophthalmology, 121 ((10)): (2053-2058). [PMID:24908203]
92. . (2014-06-24) Progress towards measles elimination – Eastern Mediterranean Region, 2008–2012.. Releve epidemiologique hebdomadaire, 89 ((24)): (257-264). [PMID:24955461]
93. Zhengping Zhang,Chunming Wang,Yinhe Zha,Wei Hu,Zhongfei Gao,Yuhui Zang,Jiangning Chen,Junfeng Zhang,Lei Dong. (2015-01-15) Corona-directed nucleic acid delivery into hepatic stellate cells for liver fibrosis therapy.. ACS nano, 9 ((3)): (2405-2419). [PMID:25587629]
94. Elise F Talsma,Hans Verhoef,Inge D Brouwer,Anne S Mburu-de Wagt,Paul J M Hulshof,Alida Melse-Boonstra. (2015-04-10) Proxy markers of serum retinol concentration, used alone and in combination, to assess population vitamin A status in Kenyan children: a cross-sectional study.. BMC medicine, 13 (): (30-30). [PMID:25856672]
95. Magalie Thierry,Bruno Pasquis,Bénédicte Buteau,Cynthia Fourgeux,Doulaye Dembele,Laurent Leclere,Ségolène Gambert-Nicot,Niyazi Acar,Alain M Bron,Catherine P Creuzot-Garcher,Lionel Bretillon. (2015-04-29) Early adaptive response of the retina to a pro-diabetogenic diet: Impairment of cone response and gene expression changes in high-fructose fed rats.. Experimental eye research, 135 (): (37-46). [PMID:25912194]
96. Shaimaa Selim,Kari Elo,Seija Jaakkola,Ninja Karikoski,Ray Boston,Tiina Reilas,Susanna S?rkij?rvi,Markku Saastamoinen,Tuomo Kokkonen. (2015-05-06) Relationships among Body Condition, Insulin Resistance and Subcutaneous Adipose Tissue Gene Expression during the Grazing Season in Mares.. PloS one, 10 ((5)): (e0125968-e0125968). [PMID:25938677]
97. Marie Vaugoyeau,Beatriz Decencière,Samuel Perret,Filiz Karadas,Sandrine Meylan,Clotilde Biard. (2015-05-13) Is oxidative status influenced by dietary carotenoid and physical activity after moult in the great tit (Parus major)?. The Journal of experimental biology, 218 ((Pt 13)): (2106-2115). [PMID:25964421]
98. Heetae Lee,GwangPyo Ko. (2016-05-18) Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome.. Scientific reports, 6 (): (25835-25835). [PMID:27180604]
99. Daniel C Cutler,Heidi Bissell,Chengdong Wang,Sam Rivera. (2019-05-24) SERUM TRACE NUTRIENT VALUES IN FOUR CAPTIVE GIANT PANDAS (AILUROPODA MELANOLEUCA).. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 50 ((1)): (176-182). [PMID:31120676]
100. Min Shen,Yujia Li,Yingqian Wang,Jiangjuan Shao,Feng Zhang,Guoping Yin,Anping Chen,Zili Zhang,Shizhong Zheng. (2021-10-05) N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells.. Redox biology, 47 (): (102151-102151). [PMID:34607160]