视黄醇
视黄酸受体配体
规格或纯度:
10mM in DMSO
有货
规格或纯度 | 10mM in DMSO |
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英文名称 | Retinol |
别名 | 全反式-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯-1-基)-2,4,6,8-壬四烯-1-醇|抗干眼醇|维生素 A 醇|维生素 A1 |
英文别名 | retinol|Vitamin A|all-trans-Retinol|68-26-8|Vitamin A1|Alphalin|Chocola A|Alphasterol|Apostavit|Aquasynth|Axerophthol|Epiteliol|Prepalin|Testavol|Veroftal|Afaxin|Agiolan|Agoncal|Anatola|Apexol|Dofsol|Myvpack|Vaflol|Vitpex|Aoral|trans-retinol|Vitamin A alc |
生化机理 | 维甲酸受体配体。维甲酸,维生素A的衍生物。调节细胞中的基因转录。棒通道抑制剂(IC 50 = 0.99μM)。 |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 |
视黄醇或维生素A醇是维生素A的主要循环形式。它不具有生物活性并可作为活性类视黄醇的一种前体。视黄醇可转化为视黄醛,然后再转化为视黄酸。All-trans及9-cis-视黄酸是核受体、视黄酸受体(RAR)和类视黄醇X受体(RXR)的配体。这些受体是多种基因的转录调控因子。 Retinol or vitamin A alcohol is the main circulating form of vitamin A. It is not biologically active. Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (in trans configuration), and an alcohol end group. |
EC号 | 200-683-7 |
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IUPAC Name | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol |
INCHI | InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+ |
InChi Key | FPIPGXGPPPQFEQ-OVSJKPMPSA-N |
Canonical SMILES | CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C |
WGK Germany | 3 |
RTECS | VH6750000 |
PubChem CID | 445354 |
分子量 | 286.45 |
Beilstein号 | 403040 |
敏感性 | 对光及湿度敏感;对空气敏感; |
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折光率 | 1.641 |
沸点 | 120-125°C |
熔点 | 61-63°C |
象形图 |
Health Hazard Harmful |
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信号词 | Danger |
危险声明 |
H319: Causes serious eye irritation H413: May cause long lasting harmful effects to aquatic life H302: Harmful if swallowed H317: May cause an allergic skin reaction H360: May damage fertility or the unborn child |
预防措施声明 | P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P270,P272,P333+P313,P362+P364,P330,P203,P264+P265,P301+P317,P318,P337+P317 |
WGK Germany | 3 |
RTECS | VH6750000 |
个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |