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基本描述
| 产品名称 | TSH |
|---|
产品规格参数
| CAS编号和信息 | rp175330 |
|---|
靶标
| Target ID | 255 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | TSH receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Glycoprotein hormone receptors | ||||||||||||||||||||||||
| 别名 | adrenergic receptor | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
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| RefSeq Protein | NP_037020 (Rn) , NP_000360 (Hs) , NP_035778 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P21463 (Rn) , P16473 (Hs) , P47750 (Mm) | ||||||||||||||||||||||||
| OMIM | 603372 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_000369 (Hs) , NM_012888 (Rn) , NM_011648 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 7253 (Hs) , 25360 (Rn) , 22095 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000165409 (Hs) , ENSMUSG00000020963 (Mm) , ENSRNOG00000003972 (Rn) | ||||||||||||||||||||||||
| Orphanet | 120320 (Hs) | ||||||||||||||||||||||||
| Protein GI | 6981680 (Rn) , 164664516 (Mm) , 217330610 (Hs) | ||||||||||||||||||||||||
| GPCRdb | tshr_human (Hs) , tshr_mouse (Mm) , tshr_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | TSHR_HUMAN (Hs) , TSHR_MOUSE (Mm) , TSHR_RAT (Rn) | ||||||||||||||||||||||||
| DrugBank Target | P16473 (Hs) | ||||||||||||||||||||||||
| CATH/Gene3D | 3.80.10.10 (N/A) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL1963 (Hs) |
关联配体
| Ligand ID | 3920 |
|---|---|
| 名称 | TSH |
| 别名 | thyroid-stimulating hormone |
| 类别 | Peptide |
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 | The drug thyrotropin alfa is a peptide heterodimer consisting of an α and β subunit and mimics the endogenous peptide hormone. |
| 配体家族 | Glycoprotein hormones |
| 相似的配体 | TSH , TSH |
| 单字母多肽序列 | |
| 三字母多肽序列 | |
| 翻译后修饰 | The production of biologically active TSH requires appropriately folded TSHβ and common α subunits that assemble to form the TSH heterodimer. |
| 化学修饰 |
产品问答
产品问答
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