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基本描述
| 产品名称 | B and T lymphocyte attenuator |
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产品规格参数
| CAS编号和信息 | rp173518 |
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数据库链接
| UniProtKB | Q7Z6A9 |
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| Wikipedia | BTLA |
| RCSB PDB Structure | 2aw2 |
| Ensembl Gene | ENSG00000186265 |
| Entrez Gene | 151888 |
| CATH/Gene3D | 2.60.40.10 |
靶标
| Target ID | 1887 | ||||||||||||||||||||||||
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| 名称 | herpes virus entry mediator | ||||||||||||||||||||||||
| 缩写名 | HVEM | ||||||||||||||||||||||||
| 家族 | Immune checkpoint catalytic receptors | ||||||||||||||||||||||||
| 别名 | SK3 | ||||||||||||||||||||||||
| 基因和蛋白信息 |
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| Ensembl Gene | ENSG00000157873 (Hs) , ENSMUSG00000042333 (Mm) , ENSRNOG00000013820 (Rn) | ||||||||||||||||||||||||
| Entrez Gene | 230979 (Mm) , 366518 (Rn) , 8764 (Hs) | ||||||||||||||||||||||||
| OMIM | 602746 (Hs) | ||||||||||||||||||||||||
| Protein GI | 23200041 (Hs) , 62543557 (Rn) , 30725810 (Mm) | ||||||||||||||||||||||||
| UniProtKB | Q92956 (Hs) |
关联配体
| Ligand ID | 4891 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | B and T lymphocyte attenuator | ||||||||||
| 别名 | B- and T-lymphocyte attenuator | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. | ||||||||||
| 配体家族 | CD molecules (ligands) | ||||||||||
| 基因/前体 |
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| 单字母多肽序列 | KESCDVQLYIKRQSEHSILAGDPFELECPVKYCANRPHVTWCKLNGTTCVKLEDRQTSWKEEKNISFFILHFEPVLPNDNGSYRCSANFQSNLIESHSTTLYVTDVKSASERPSKDEMASRPWLLYRLLPLGGLPLLITTCFCLFCCLRRHQGKQNELSDTAGREINLVDAHLKSEQTEASTRQNSQVLLSETGIYDNDPDLCFRMQEGSEVYSNPCLEENKPGIVYASLNHSVIGPNSRLARNVKEAPTEYASICVRS | ||||||||||
| 三字母多肽序列 | |||||||||||
| 翻译后修饰 | Predicted N-linked glcosylation of asparagine residues at positions 45, 64 and 80; disulphide bond formation between cysteine residues at positions 4 and 33, 28 and 85, and 42 and 49 | ||||||||||
| 化学修饰 |
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产品问答
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