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基本描述
| 英文名称 | ZK 93423 hydrochloride |
|---|---|
| 英文别名 | 4-(Methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester hydrochloride |
| 储存温度 | 室温,干燥 |
| 运输条件 | 常规运输 |
| 产品介绍 |
ZK 93423盐酸盐是一种强效的苯二氮卓激动剂。对包含α1-，α2-，α3-和α5-亚基的GABA | A |受体非选择性。 ZK 93423 hydrochloride is a potent benzodiazepine agonist. Non-selective with GABA|A|receptors containing α1-, α2-, α3- and α5-subunits. |
名称和标识符
| IUPAC Name | ethyl 4-(methoxymethyl)-6-phenylmethoxy-9H-pyrido[3,4-b]indole-3-carboxylate |
|---|---|
| INCHI | InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,25H,3,13-14H2,1-2H3 |
| InChi Key | ALBKMJDFBZVHAK-UHFFFAOYSA-N |
| Canonical SMILES | CCOC(=O)C1=NC=C2C(=C1COC)C3=C(N2)C=CC(=C3)OCC4=CC=CC=C4 |
| PubChem CID | 121926 |
| 分子量 | 390.43 |
数据库链接
| PubChem CID | 121926 |
|---|---|
| ChEMBL Ligand | CHEMBL1518572 |
| CAS Registry No. | 83910-44-5 |
| Wikipedia | ZK-93423 |
化学和物理性质
| 溶解性 | Soluble to 30 mM in DMSO and to 5 mM in Ethanol |
|---|
关联配体
| Ligand ID | 4346 |
|---|---|
| 名称 | ZK93423 |
| 别名 | ZK-93423 |
| 类别 | Synthetic organic |
| 学名 | ethyl 6-(benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylate |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. |
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