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VEGFD
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基本描述
| 产品名称 | VEGFD |
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产品规格参数
| CAS编号和信息 | rp175380 |
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数据库链接
| UniProtKB | O43915 |
|---|---|
| Wikipedia | C-fos_induced_growth_factor |
| Ensembl Gene | ENSG00000165197 |
| CATH/Gene3D | 2.10.90.10 |
靶标
| Target ID | 1814 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | fms related receptor tyrosine kinase 4 | ||||||||||||||||||||||||
| 缩写名 | VEGFR-3 | ||||||||||||||||||||||||
| 家族 | Type IV RTKs: VEGF (vascular endothelial growth factor) receptor family | ||||||||||||||||||||||||
| 别名 | EBRT2 | ||||||||||||||||||||||||
| 基因和蛋白信息 |
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| Ensembl Gene | ENSG00000037280 (Hs) , ENSMUSG00000020357 (Mm) , ENSRNOG00000002511 (Rn) | ||||||||||||||||||||||||
| Entrez Gene | 14257 (Mm) , 114110 (Rn) , 2324 (Hs) | ||||||||||||||||||||||||
| OMIM | 136352 (Hs) | ||||||||||||||||||||||||
| Protein GI | 16758466 (Rn) , 104294888 (Hs) , 6679813 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P35916 (Hs) , P35917 (Mm) , Q91ZT1 (Rn) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_002020 (Hs) , NM_008029 (Mm) , NM_053652 (Rn) | ||||||||||||||||||||||||
| RefSeq Protein | NP_002011 (Hs) , NP_032055 (Mm) , NP_446104 (Rn) | ||||||||||||||||||||||||
| Orphanet | 121872 (Hs) | ||||||||||||||||||||||||
| DrugBank Target | P35916 (Hs) | ||||||||||||||||||||||||
| CATH/Gene3D | 2.60.40.10 (N/A) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL4758 (Mm) , CHEMBL1955 (Hs) |
关联配体
| Ligand ID | 5088 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | VEGFD | ||||||||||
| 别名 | c-fos induced growth factor | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. | ||||||||||
| 配体家族 | Vascular endothelial growth factor (VEGF) family ligands | ||||||||||
| 基因/前体 |
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| 单字母多肽序列 | FAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRR | ||||||||||
| 三字母多肽序列 | |||||||||||
| 翻译后修饰 | Homodimer formed by interchain disulphide bonds between cysteine residues at positions 48 and 57; further disulphide bonds formed between cysteine residues at positions 23 and 65, 54 and 101, and 58 and 103. N-linked glycosylation of asparagine residues at positions 67 and 97; predicted N-linked glycosylation of asparagine at 199 | ||||||||||
| 化学修饰 |
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产品问答
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