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VEGFB
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基本描述
| 产品名称 | VEGFB |
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产品规格参数
| CAS编号和信息 | rp175378 |
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数据库链接
| UniProtKB | P49765 |
|---|---|
| Wikipedia | VEGFB |
| RCSB PDB Structure | 2c7w |
| Ensembl Gene | ENSG00000173511 |
| DrugBank Target | P49765 |
| CATH/Gene3D | 2.10.90.10 |
靶标
| Target ID | 1812 | ||||||||||||||||||||||||
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| 名称 | fms related receptor tyrosine kinase 1 | ||||||||||||||||||||||||
| 缩写名 | VEGFR-1 | ||||||||||||||||||||||||
| 家族 | Type IV RTKs: VEGF (vascular endothelial growth factor) receptor family | ||||||||||||||||||||||||
| 别名 | EBRT2 | ||||||||||||||||||||||||
| 基因和蛋白信息 |
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| Ensembl Gene | ENSG00000102755 (Hs) , ENSMUSG00000029648 (Mm) , ENSRNOG00000000940 (Rn) | ||||||||||||||||||||||||
| Entrez Gene | 14254 (Mm) , 54251 (Rn) , 2321 (Hs) | ||||||||||||||||||||||||
| OMIM | 165070 (Hs) | ||||||||||||||||||||||||
| Protein GI | 11276093 (Rn) , 34328180 (Mm) , 229892302 (Hs) | ||||||||||||||||||||||||
| UniProtKB | P17948 (Hs) , P35969 (Mm) , P53767 (Rn) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_001159920 (Hs) , NM_010228 (Mm) , NM_019306 (Rn) | ||||||||||||||||||||||||
| RefSeq Protein | NP_001153392 (Hs) , NP_034358 (Mm) , NP_062179 (Rn) | ||||||||||||||||||||||||
| DrugBank Target | P17948 (Hs) | ||||||||||||||||||||||||
| CATH/Gene3D | 2.60.40.10 (N/A) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL1868 (Hs) , CHEMBL3516 (Mm) |
关联配体
| Ligand ID | 5086 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | VEGFB | ||||||||||
| 别名 | VEGF-related factor | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 | The active peptide is a homodimer linked by disulphide bonds | ||||||||||
| 配体家族 | Vascular endothelial growth factor (VEGF) family ligands | ||||||||||
| 基因/前体 |
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| 单字母多肽序列 | PVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA | ||||||||||
| 三字母多肽序列 | |||||||||||
| 翻译后修饰 | Homodimer formed by interchain disulphide bonds between cysteine residues at positions 51 and 60; further disulphide bonds formed between cysteine residues at positions 26 and 68, 57 and 102, and 61 and 103. | ||||||||||
| 化学修饰 |
产品问答
产品问答
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