产品名称 | LH |
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CAS编号和信息 | rp174455 |
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DrugBank Ligand | DB00044 |
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Target ID | 254 | ||||||||||||||||||||||||
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名称 | LH receptor | ||||||||||||||||||||||||
缩写名 | SHP2 | ||||||||||||||||||||||||
家族 | Glycoprotein hormone receptors | ||||||||||||||||||||||||
别名 | adrenergic receptor | ||||||||||||||||||||||||
基因和蛋白信息 |
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RefSeq Protein | NP_037110 (Rn) , NP_000224 (Hs) , NP_038610 (Mm) | ||||||||||||||||||||||||
UniProtKB | P16235 (Rn) , P22888 (Hs) , P30730 (Mm) | ||||||||||||||||||||||||
OMIM | 152790 (Hs) | ||||||||||||||||||||||||
RefSeq Nucleotide | NM_000233 (Hs) , NM_012978 (Rn) , NM_013582 (Mm) | ||||||||||||||||||||||||
Entrez Gene | 3973 (Hs) , 25477 (Rn) , 16867 (Mm) | ||||||||||||||||||||||||
Ensembl Gene | ENSG00000138039 (Hs) , ENSMUSG00000024107 (Mm) , ENSRNOG00000016712 (Rn) | ||||||||||||||||||||||||
Orphanet | 123048 (Hs) | ||||||||||||||||||||||||
Protein GI | 6981160 (Rn) , 7305233 (Mm) , 106067657 (Hs) | ||||||||||||||||||||||||
GPCRdb | lshr_human (Hs) , lshr_mouse (Mm) , lshr_rat (Rn) | ||||||||||||||||||||||||
UniProtKB ID/Entry name | LSHR_HUMAN (Hs) , LSHR_MOUSE (Mm) , LSHR_RAT (Rn) | ||||||||||||||||||||||||
DrugBank Target | P22888 (Hs) | ||||||||||||||||||||||||
CATH/Gene3D | 3.80.10.10 (N/A) | ||||||||||||||||||||||||
ChEMBL Target | CHEMBL4523213 (Mm) , CHEMBL1854 (Hs) , CHEMBL2456 (Rn) |
Ligand ID | 1159 |
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名称 | LH |
别名 | luteinising hormone |
类别 | Peptide |
学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
评价 | The approved drug lutropin alfa (INN) is the recombinant form of human LH and is composed of two subunits (α = 92 amino acids, β = 121 amino acids). |
配体家族 | Glycoprotein hormones |
相似的配体 | LH , LH |
单字母多肽序列 | |
三字母多肽序列 | |
翻译后修饰 |
The production of biologically active LH requires appropriately folded and glycosylated LHβ and common α subunits that assemble to form the active LH heterodimer |
化学修饰 |