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IL-4
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基本描述
| 产品名称 | IL-4 |
|---|
产品规格参数
| CAS编号和信息 | rp174312 |
|---|
数据库链接
| UniProtKB | P05112 |
|---|---|
| Wikipedia | Interleukin_4 |
| RCSB PDB Structure | 2INT |
| Ensembl Gene | ENSG00000113520 |
| Immunopaedia Search | IL-4 |
靶标
| Target ID | 2298 |
|---|---|
| 名称 | Interleukin-4 receptor type I |
| 缩写名 | SHP2 |
| 家族 | IL-2 receptor family |
| 别名 | MAS1 oncogene-like |
| Target ID | 2299 |
|---|---|
| 名称 | Interleukin-4 receptor type II |
| 缩写名 | SHP2 |
| 家族 | IL-2 receptor family |
| 别名 | MAS1 oncogene-like |
关联配体
| Ligand ID | 4996 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | IL-4 | ||||||||||
| 别名 | interleukin-4 | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 |
IL-4 shares sequence and structural homology with |
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| 配体家族 | Interleukins | ||||||||||
| 基因/前体 |
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| 单字母多肽序列 | HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS | ||||||||||
| 三字母多肽序列 | |||||||||||
| 翻译后修饰 | N-linked glycosylation of asparagine residue at position 38; disulphide bond formation between cysteine residues at positions 3 and 127, 24 and 65, and 46 and 99 | ||||||||||
| 化学修饰 |
参考文献
| 1. Sokol CL, Barton GM, Farr AG, Medzhitov R. (2008) A mechanism for the initiation of allergen-induced T helper type 2 responses.. Nat Immunol, 9 (3): (310-8). [PMID:18300366] |
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