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ectodysplasin A1
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基本描述
| 产品名称 | ectodysplasin A1 |
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产品规格参数
| CAS编号和信息 | rp173943 |
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数据库链接
| UniProtKB | Q92838 |
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| CATH/Gene3D | 2.60.120.40 |
| Ensembl Gene | ENSG00000158813 |
靶标
| Target ID | 2325 | ||||||||||||||||||||||||
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| 名称 | ectodysplasin 1, anhidrotic receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Tumour necrosis factor (TNF) receptor family | ||||||||||||||||||||||||
| 基因和蛋白信息 |
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| UniProtKB | Q9UNE0 (Hs) , Q9R187 (Mm) | ||||||||||||||||||||||||
| OMIM | 604095 (Hs) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000135960 (Hs) , ENSMUSG00000003227 (Mm) , ENSRNOG00000028598 (Rn) | ||||||||||||||||||||||||
| Entrez Gene | 10913 (Hs) , 13608 (Mm) , 365581 (Rn) | ||||||||||||||||||||||||
| Protein GI | 21263571 (Mm) , 21263572 (Hs) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL1250376 (Hs) |
关联配体
| Ligand ID | 6144 | ||||||||||
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| 名称 | ectodysplasin A1 | ||||||||||
| 别名 | ectodysplasin-A isoform 1 | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 | Forms a homotrimeric structure | ||||||||||
| 配体家族 | Tumor necrosis factor superfamily ligands | ||||||||||
| 基因/前体 |
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| 单字母多肽序列 | MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKIAVKMVHADISINMSKHTTFFGAIRLGEAPAS | ||||||||||
| 三字母多肽序列 | |||||||||||
| 翻译后修饰 | Predicated N-linked glycosylation of asparagine residues at positions 154 and 213 of the amino acid sequence. | ||||||||||
| 化学修饰 |
产品问答
产品问答
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