首页
400-620-6333
切换导航
搜索
基本描述
| 产品名称 | CXCL1 |
|---|
产品规格参数
| CAS编号和信息 | rp173755 |
|---|
数据库链接
| UniProtKB | P09341 |
|---|---|
| RefSeq Protein | NP_001502 |
| Wikipedia | CXCL1 |
| OMIM | 155730 |
| Ensembl Gene | ENSG00000163739 |
靶标
| Target ID | 69 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | CXCR2 | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Chemokine receptors | ||||||||||||||||||||||||
| 别名 | m1 | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
||||||||||||||||||||||||
| RefSeq Protein | NP_058879 (Rn) , NP_001548 (Hs) , NP_034039 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P35407 (Rn) , P25025 (Hs) , P35343 (Mm) | ||||||||||||||||||||||||
| OMIM | 146928 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_001557 (Hs) , NM_017183 (Rn) , NM_009909 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 3579 (Hs) , 29385 (Rn) , 12765 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000180871 (Hs) , ENSMUSG00000026180 (Mm) , ENSRNOG00000063618 (Rn) | ||||||||||||||||||||||||
| Protein GI | 8393600 (Rn) , 269973859 (Hs) , 6753456 (Mm) | ||||||||||||||||||||||||
| GPCRdb | cxcr2_human (Hs) , cxcr2_mouse (Mm) , cxcr2_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | CXCR2_HUMAN (Hs) , CXCR2_MOUSE (Mm) , CXCR2_RAT (Rn) | ||||||||||||||||||||||||
| dbSNP | rs1126579 (Hs) , rs1126579 (Hs) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL4105830 (Mm) , CHEMBL2434 (Hs) |
关联配体
| Ligand ID | 819 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | CXCL1 | ||||||||||
| 别名 | GROα | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
||||||||||
| 评价 |
CXCL1 is a C-X-C motif chemokine expressed by macrophages, neutrophils and epithelial cells, that acts via the chemokine receptor CXCR2. CXCL1 is expressed by keratinocytes and endothelial cells at sites of epithelialization and neovascularization in the process of wound healing |
||||||||||
| 配体家族 | Chemokines | ||||||||||
| 基因/前体 |
|
||||||||||
| 单字母多肽序列 | ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN | ||||||||||
| 三字母多肽序列 | Ala-Ser-Val-Ala-Thr-Glu-Leu-Arg-Cys-Gln-Cys-Leu-Gln-Thr-Leu-Gln-Gly-Ile-His-Pro-Lys-Asn-Ile-Gln-Ser-Val-Asn-Val-Lys-Ser-Pro-Gly-Pro-His-Cys-Ala-Gln-Thr-Glu-Val-Ile-Ala-Thr-Leu-Lys-Asn-Gly-Arg-Lys-Ala-Cys-Leu-Asn-Pro-Ala-Ser-Pro-Ile-Val-Lys-Lys-Ile-Ile-Glu-Lys-Met-Leu-Asn-Ser-Asp-Lys-Ser-Asn | ||||||||||
| 翻译后修饰 | |||||||||||
| 化学修饰 |
参考文献
| 1. Devalaraja RM, Nanney LB, Du J, Qian Q, Yu Y, Devalaraja MN, Richmond A. (2000) Delayed wound healing in CXCR2 knockout mice.. J Invest Dermatol, 115 (2): (234-44). [PMID:10951241] |
产品问答
产品问答
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）