产品名称 | CD40 ligand |
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CAS编号和信息 | rp173690 |
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UniProtKB | P29965 |
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Wikipedia | CD40_ligand |
RCSB PDB Structure | 1aly |
Ensembl Gene | ENSG00000102245 |
CATH/Gene3D | 2.60.120.40 |
Target ID | 1874 | ||||||||||||||||||||||||
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名称 | CD40 | ||||||||||||||||||||||||
缩写名 | SHP2 | ||||||||||||||||||||||||
家族 | Immune checkpoint catalytic receptors | ||||||||||||||||||||||||
别名 | SK3 | ||||||||||||||||||||||||
基因和蛋白信息 |
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Ensembl Gene | ENSG00000101017 (Hs) , ENSMUSG00000017652 (Mm) , ENSRNOG00000018488 (Rn) | ||||||||||||||||||||||||
Entrez Gene | 21939 (Mm) , 171369 (Rn) , 958 (Hs) | ||||||||||||||||||||||||
OMIM | 109535 (Hs) | ||||||||||||||||||||||||
Protein GI | 23312371 (Hs) , 70608202 (Mm) , 68534951 (Rn) | ||||||||||||||||||||||||
UniProtKB | P25942 (Hs) , P27512 (Mm) | ||||||||||||||||||||||||
ChEMBL Target | CHEMBL1250358 (Hs) |
Ligand ID | 5077 | ||||||||||
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名称 | CD40 ligand | ||||||||||
别名 | CD40 ligand, membrane form | ||||||||||
类别 | Peptide | ||||||||||
学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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评价 | The CD40 ligand precursor is also cleaved into a soluble form of the ligand | ||||||||||
配体家族 | CD molecules (ligands) | ||||||||||
基因/前体 |
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单字母多肽序列 | MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAVYLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNKEETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL | ||||||||||
三字母多肽序列 | |||||||||||
翻译后修饰 | N-linked glycosylation of asparagine at position 240; predicted phosphothreonine at position 4; predicted disulphide bond formation between cysteine residues at positions 178 and 218 | ||||||||||
化学修饰 |