首页
400-620-6333
CCL3
功能和特点
有货
切换导航
搜索
基本描述
| 产品名称 | CCL3 |
|---|
产品规格参数
| CAS编号和信息 | rp173675 |
|---|
数据库链接
| OMIM | 182283 |
|---|---|
| RefSeq Protein | NP_002974 |
| UniProtKB | P10147 |
| Ensembl Gene | ENSG00000006075 |
关联配体
| Ligand ID | 756 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | CCL3 | ||||||||||
| 别名 | MIP-1α | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
||||||||||
| 评价 |
CCL3 is a CC family chemokine more commonly referred to as macrophage inflammatory protein-1α or MIP-1α. It acts in a dimer with CCL4 (MIP-1β) |
||||||||||
| 配体家族 | Chemokines | ||||||||||
| 基因/前体 |
|
||||||||||
| 单字母多肽序列 | SLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA | ||||||||||
| 三字母多肽序列 | Ser-Leu-Ala-Ala-Asp-Thr-Pro-Thr-Ala-Cys-Cys-Phe-Ser-Tyr-Thr-Ser-Arg-Gln-Ile-Pro-Gln-Asn-Phe-Ile-Ala-Asp-Tyr-Phe-Glu-Thr-Ser-Ser-Gln-Cys-Ser-Lys-Pro-Gly-Val-Ile-Phe-Leu-Thr-Lys-Arg-Ser-Arg-Gln-Val-Cys-Ala-Asp-Pro-Ser-Glu-Glu-Trp-Val-Gln-Lys-Tyr-Val-Ser-Asp-Leu-Glu-Leu-Ser-Ala | ||||||||||
| 翻译后修饰 | 1 N-terminally truncated form is found (MIP-1-alpha(4-69)) | ||||||||||
| 化学修饰 |
产品问答
产品问答
参考文献
| 1. Li K, Wang B, Sui H, Liu S, Yao S, Guo L, Mao D. (2009) Polymorphisms of the macrophage inflammatory protein 1 alpha and ApoE genes are associated with ulcerative colitis.. Int J Colorectal Dis, 24 (1): (13-7). [PMID:18762952] |
| 2. Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD et al.. (2010) Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme.. EMBO J, 29 (23): (3952-66). [PMID:20959807] |
| 3. Sherry B, Tekamp-Olson P, Gallegos C, Bauer D, Davatelis G, Wolpe SD, Masiarz F, Coit D, Cerami A. (1988) Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta.. J Exp Med, 168 (6): (2251-9). [PMID:3058856] |
| 4. A-González N, Castrillo A. (2011) Liver X receptors as regulators of macrophage inflammatory and metabolic pathways.. Biochim Biophys Acta, 1812 (8): (982-94). [PMID:21193033] |
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）