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BIM 23197
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基本描述
| 产品名称 | BIM 23197 |
|---|
产品规格参数
| CAS编号和信息 | 168016-90-8 |
|---|
数据库链接
| CAS Registry No. | 168016-90-8 |
|---|---|
| GPCRdb Ligand | BIM 23197 |
关联配体
| Ligand ID | 2041 |
|---|---|
| 名称 | BIM 23197 |
| 类别 | Peptide |
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. |
| 单字母多肽序列 | FCYWKXCT |
| 三字母多肽序列 | Hepes-D-Phe-c[Cys-Tyr-D-Trp-Lys-Abu-Cys]-Thr-NH2 |
| 翻译后修饰 | |
| 化学修饰 | The peptide is tagged with buffering agent HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid). C-terminal cysteine residue is amidated; disulphide bond formation between cysteine residues at positions 2 and 7. Abu is 2-amino-butanoic acid |
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