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基本描述
| 产品名称 | BIM 23127 |
|---|
产品规格参数
| CAS编号和信息 | 179188-73-9 |
|---|
数据库链接
| CAS Registry No. | 179188-73-9 |
|---|---|
| GPCRdb Ligand | BIM 23127 |
靶标
| Target ID | 365 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | UT receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Urotensin receptor | ||||||||||||||||||||||||
| 别名 | THC receptor | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
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| RefSeq Protein | NP_065412 (Rn) , NP_061822 (Hs) , NP_663415 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P49684 (Rn) , Q9UKP6 (Hs) , Q8VIH9 (Mm) | ||||||||||||||||||||||||
| OMIM | 600896 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_018949 (Hs) , NM_020537 (Rn) , NM_145440 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 2837 (Hs) , 57305 (Rn) , 217369 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000181408 (Hs) , ENSMUSG00000039321 (Mm) , ENSRNOG00000036669 (Rn) | ||||||||||||||||||||||||
| Protein GI | 10120496 (Rn) , 21703878 (Mm) , 9506745 (Hs) | ||||||||||||||||||||||||
| GPCRdb | ur2r_human (Hs) , ur2r_mouse (Mm) , ur2r_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | UR2R_HUMAN (Hs) , UR2R_MOUSE (Mm) , UR2R_RAT (Rn) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL2346494 (Mm) , CHEMBL3764 (Hs) , CHEMBL4921 (Rn) |
关联配体
| Ligand ID | 2162 |
|---|---|
| 名称 | BIM 23127 |
| 类别 | Peptide |
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. |
| 单字母多肽序列 | ACYWXVCA |
| 三字母多肽序列 | D-Nal-Cys-Tyr-D-Trp-Orn-Val-Cys-Nal-NH2 |
| 翻译后修饰 | |
| 化学修饰 | Tryptophan residue is D-Trp; residue 5 is ornithine, disulphide bond between cysteine residues at positions 2 and 7; Nal=β-2-napthyl-L-alanine-NH2. N-termimal residue is the D-isomer |
产品问答
产品问答
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