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B1-27

有货

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
rp173512-500μg	500μg	期货
rp173512-1mg	1mg	期货

查看相关系列

RXFP3 Agonist

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基本描述

产品名称	B1-27

产品规格参数

CAS编号和信息	rp173512

数据库链接

GPCRdb Ligand	B1-27

靶标

Target ID

353

名称

RXFP3

缩写名

SHP2

家族

Relaxin family peptide receptors

别名

GPCR6A

基因和蛋白信息

Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Rat	7	476	2q16	Rxfp3	relaxin family peptide receptor 3
Human	7	469	5p13.2	RXFP3	relaxin family peptide receptor 3
Mouse	7	472	15 A1	Rxfp3	relaxin family peptide receptor 3

RefSeq Protein

NP_001008311 (Rn) , NP_057652 (Hs) , NP_848832 (Mm)

UniProtKB

Q5Y986 (Rn) , Q9NSD7 (Hs) , Q8BGE9 (Mm)

OMIM

609445 (Hs)

RefSeq Nucleotide

NM_016568 (Hs) , NM_001008310 (Rn) , NM_178717 (Mm)

Entrez Gene

51289 (Hs) , 294807 (Rn) , 239336 (Mm)

Ensembl Gene

ENSG00000182631 (Hs) , ENSMUSG00000060735 (Mm) , ENSRNOG00000023126 (Rn)

Protein GI

56605940 (Rn) , 7706103 (Hs) , 30520143 (Mm)

GPCRdb

rl3r1_human (Hs) , rl3r1_mouse (Mm) , q5y986_rat (Rn)

UniProtKB ID/Entry name

RL3R1_HUMAN (Hs) , RL3R1_MOUSE (Mm) , Q5Y986_RAT (Rn)

dbSNP

rs7702361 (Hs) , rs42868 (Hs)

ChEMBL Target

CHEMBL1628472 (Hs)

关联配体

Ligand ID	11459
名称	B1-27
别名	analog 2 [PMID: 32133341]
类别	Peptide
学名	4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
生物活性评价	The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).
评价	B1-27 is relaxin-3 B-chain analogue .
单字母多肽序列	RAAPYGVRLCGREFIRAVIFTCGGSRW
三字母多肽序列	Arg-Ala-Ala-Pro-Tyr-Gly-Val-Arg-Leu-Cys-Gly-Arg-Glu-Phe-Ile-Arg-Ala-Val-Ile-Phe-Thr-Cys-Gly-Gly-Ser-Arg-Trp-OH
翻译后修饰
化学修饰

参考文献

1. Lee HS, Postan M, Song A, Clark RJ, Bathgate RAD, Haugaard-Kedstr?m LM, Rosengren KJ. (2020) Development of Relaxin-3 Agonists and Antagonists Based on Grafted Disulfide-Stabilized Scaffolds.. Front Chem, 8 (13): (87). [PMID:32133341]