首页
400-620-6333
agouti-related protein
有货
切换导航
搜索
基本描述
| 产品名称 | agouti-related protein |
|---|
产品规格参数
| CAS编号和信息 | rp173399 |
|---|
数据库链接
| Ensembl Gene | ENSG00000159723 |
|---|---|
| Entrez Gene | 181 |
靶标
| Target ID | 284 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | MC3 receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Melanocortin receptors | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
||||||||||||||||||||||||
| RefSeq Protein | NP_001020441 (Rn) , NP_063941 (Hs) , NP_032587 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P32244 (Rn) , P41968 (Hs) , P33033 (Mm) | ||||||||||||||||||||||||
| OMIM | 155540 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_019888 (Hs) , NM_001025270 (Rn) , NM_008561 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 4159 (Hs) , 29310 (Rn) , 17201 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000124089 (Hs) , ENSMUSG00000038537 (Mm) , ENSRNOG00000004451 (Rn) | ||||||||||||||||||||||||
| Orphanet | 220900 (Hs) | ||||||||||||||||||||||||
| Protein GI | 6678822 (Mm) , 148356234 (Rn) , 170671732 (Hs) | ||||||||||||||||||||||||
| GPCRdb | mc3r_mouse (Mm) , mc3r_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | MC3R_HUMAN (Hs) , MC3R_MOUSE (Mm) , MC3R_RAT (Rn) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL4644 (Hs) , CHEMBL4023 (Rn) , CHEMBL4774 (Mm) |
| Target ID | 285 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | MC4 receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Melanocortin receptors | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
||||||||||||||||||||||||
| RefSeq Protein | NP_037231 (Rn) , NP_005903 (Hs) , NP_058673 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P70596 (Rn) , P32245 (Hs) , P56450 (Mm) | ||||||||||||||||||||||||
| OMIM | 155541 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_005912 (Hs) , NM_013099 (Rn) , NM_016977 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 4160 (Hs) , 25635 (Rn) , 17202 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000166603 (Hs) , ENSMUSG00000047259 (Mm) , ENSRNOG00000018692 (Rn) | ||||||||||||||||||||||||
| Orphanet | 168091 (Hs) | ||||||||||||||||||||||||
| Protein GI | 25742776 (Rn) , 85861190 (Mm) , 119508433 (Hs) | ||||||||||||||||||||||||
| GPCRdb | mc4r_human (Hs) , mc4r_mouse (Mm) , mc4r_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | MC4R_HUMAN (Hs) , MC4R_MOUSE (Mm) , MC4R_RAT (Rn) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL2700 (Rn) , CHEMBL3719 (Mm) , CHEMBL259 (Hs) |
| Target ID | 286 | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | MC5 receptor | ||||||||||||||||||||||||
| 缩写名 | SHP2 | ||||||||||||||||||||||||
| 家族 | Melanocortin receptors | ||||||||||||||||||||||||
| 基因和蛋白信息 |
|
||||||||||||||||||||||||
| RefSeq Protein | NP_037314 (Rn) , NP_005904 (Hs) , NP_038624 (Mm) | ||||||||||||||||||||||||
| UniProtKB | P35345 (Rn) , P33032 (Hs) , P41149 (Mm) | ||||||||||||||||||||||||
| OMIM | 600042 (Hs) | ||||||||||||||||||||||||
| RefSeq Nucleotide | NM_005913 (Hs) , NM_013182 (Rn) , NM_013596 (Mm) | ||||||||||||||||||||||||
| Entrez Gene | 4161 (Hs) , 25726 (Rn) , 17203 (Mm) | ||||||||||||||||||||||||
| Ensembl Gene | ENSG00000176136 (Hs) , ENSMUSG00000007480 (Mm) , ENSRNOG00000016685 (Rn) | ||||||||||||||||||||||||
| Protein GI | 6981190 (Rn) , 5174535 (Hs) , 158533997 (Mm) | ||||||||||||||||||||||||
| GPCRdb | mc5r_human (Hs) , mc5r_mouse (Mm) , mc5r_rat (Rn) | ||||||||||||||||||||||||
| UniProtKB ID/Entry name | MC5R_HUMAN (Hs) , MC5R_MOUSE (Mm) , MC5R_RAT (Rn) | ||||||||||||||||||||||||
| ChEMBL Target | CHEMBL4489 (Mm) , CHEMBL2701 (Rn) , CHEMBL4608 (Hs) |
关联配体
| Ligand ID | 1335 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | agouti-related protein | ||||||||||
| 别名 | agouti-related peptide | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
||||||||||
| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. | ||||||||||
| 配体家族 | Neuropeptides | ||||||||||
| 基因/前体 |
|
||||||||||
| 单字母多肽序列 | AQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT | ||||||||||
| 三字母多肽序列 | Ala-Gln-Met-Gly-Leu-Ala-Pro-Met-Glu-Gly-Ile-Arg-Arg-Pro-Asp-Gln-Ala-Leu-Leu-Pro-Glu-Leu-Pro-Gly-Leu-Gly-Leu-Arg-Ala-Pro-Leu-Lys-Lys-Thr-Thr-Ala-Glu-Gln-Ala-Glu-Glu-Asp-Leu-Leu-Gln-Glu-Ala-Gln-Ala-Leu-Ala-Glu-Val-Leu-Asp-Leu-Gln-Asp-Arg-Glu-Pro-Arg-Ser-Ser-Arg-Arg-Cys-Val-Arg-Leu-His-Glu-Ser-Cys-Leu-Gly-Gln-Gln-Val-Pro-Cys-Cys-Asp-Pro-Cys-Ala-Thr-Cys-Tyr-Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys-Tyr-Cys-Arg-Lys-Leu-Gly-Thr-Ala-Met-Asn-Pro-Cys-Ser-Arg-Thr | ||||||||||
| 翻译后修饰 | Disulfide bonds are formed between cysteine residues 67 and 82, 74 and 88, 81 and 99, 85 and 109, 90 and 97. | ||||||||||
| 化学修饰 |
产品问答
产品问答
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）