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4-1BB ligand

有货

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
rp173340-500μg	500μg	期货
rp173340-1mg	1mg	期货

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4-1BB

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基本描述

产品名称	4-1BB ligand

产品规格参数

CAS编号和信息	rp173340

数据库链接

UniProtKB	P41273
Wikipedia	4-1BB_ligand
RCSB PDB Structure	2X29
Ensembl Gene	ENSG00000125657
CATH/Gene3D	2.60.120.40

靶标

Target ID

1878

名称

4-1BB

缩写名

SHP2

家族

Tumour necrosis factor (TNF) receptor family

基因和蛋白信息

Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Human	1	255	1p36.23	TNFRSF9	TNF receptor superfamily member 9
Mouse	1	256	4 81.52 cM	Tnfrsf9	tumor necrosis factor receptor superfamily, member 9
Rat	1	308	9	Tnfrsf9	TNF receptor superfamily member 9

Ensembl Gene

ENSG00000049249 (Hs) , ENSMUSG00000028965 (Mm) , ENSRNOG00000036942 (Rn)

Entrez Gene

21942 (Mm) , 500590 (Rn) , 3604 (Hs)

OMIM

602250 (Hs)

Protein GI

5730095 (Hs) , 117422439 (Mm) , 71043922 (Rn)

UniProtKB

Q07011 (Hs) , P20334 (Mm)

RefSeq Protein

NP_003802 (Hs) , NP_033430 (Mm) , NP_852049 (Rn)

RefSeq Nucleotide

NM_003811 (Hs) , NM_009404 (Mm) , NM_181384 (Rn)

ChEMBL Target

CHEMBL3712857 (Hs)

关联配体

Ligand ID

5081

名称

4-1BB ligand

别名

4-1BB ligand

类别

Peptide

学名

4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

生物活性评价

The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).

评价

Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth.

配体家族

Tumor necrosis factor superfamily ligands

基因/前体

Gene symbol	Gene name	Precursor protein name	Species	别名
TNFSF9	TNF superfamily member 9	prepro-tumor necrosis factor ligand superfamily member 9	Human	4-1BB-L, receptor 4-1BB ligand, homolog of mouse 4-1BB-L, tumor necrosis factor (ligand) superfamily, member 9, tumor necrosis factor superfamily member 9

单字母多肽序列

MEYASDASLDPEAPWPPAPRARACRVLPWALVAGLLLLLLLAAACAVFLACPWAVSGARASPGSAASPRLREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE

三字母多肽序列

翻译后修饰

化学修饰