规格或纯度 | ≥98% |
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英文名称 | Nebivolol |
英文别名 | Nebilet |
储存温度 | 2-8°C储存,干燥 |
运输条件 | 冰袋运输 |
IUPAC Name | 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol |
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INCHI | InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2 |
InChi Key | KOHIRBRYDXPAMZ-UHFFFAOYSA-N |
Canonical SMILES | C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O |
PubChem CID | 71301 |
分子量 | 405.44 |
DrugBank Ligand | DB04861 |
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PubChem CID | 71301 |
CAS Registry No. | 99200-09-6 |
ChEMBL Ligand | CHEMBL434394 |
Wikipedia | nebivolol |
PEP | nebivolol |
Reactome Reaction | R-HSA-9609310 |
Reactome Drug | R-ALL-9610987 |
DrugCentral Ligand | 1887 |
GPCRdb Ligand | nebivolol |
象形图 |
Health Hazard Harmful |
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信号词 | Warning |
危险声明 |
H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed H332: Harmful if inhaled H361: Suspected of damaging fertility or the unborn child |
预防措施声明 | P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P203,P264+P265,P301+P317,P318,P317,P337+P317,P332+P317,P319 |
Ligand ID | 7246 |
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名称 | nebivolol |
别名 | Bystolic® |
类别 | Synthetic organic |
学名 | 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol |
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
评价 |
Nebivolol is a β-blocker, selective for β1-adrenoceptors. Marketed formulations may contain nebivolol hydrochloride (PubChem CID ). |