英文名称 | MRS4162-BODIPY conjugate |
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别名 | BODIPY 630/650 conjugate 28 |
英文别名 | BODIPY 630/650 conjugate 28 |
INCHI | InChI=1S/C56H67BF2N11O20P3S/c58-57(59)69-41(16-17-42(69)33-43-18-23-46(70(43)57)48-8-5-32-94-48)15-10-39-13-21-45(22-14-39)84-36-51(72)61-26-3-1-2-9-50(71)60-27-6-29-67-34-40(64-66-67)24-28-62-52(73)37-85-44-19-11-38(12-20-44)7-4-31-86-65-49-25-30-68(56(76)63-49)55-54(75)53(74)47(88-55)35-87-92(80,81)90-93(82,83)89-91(77,78)79/h5,8,10-23,25,30,32-34,47,53-55,74-75H,1-4,6-7,9,24,26-29,31,35-37H2,(H,60,71)(H,61,72)(H,62,73)(H,80,81)(H,82,83)(H,63,65,76)(H2,77,78,79)/b15-10+/t47-,53-,54-,55-/m1/s1 |
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InChi Key | IKFGJXBDIZQEHP-NJFIWEGUSA-N |
Canonical SMILES | O=C(COc1ccc(cc1)CCCONc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)COP(=O)(OP(=O)(OP(=O)(O)O)O)O)NCCc1nnn(c1)CCCNC(=O)CCCCCNC(=O)COc1ccc(cc1)/C=C/c1ccc2n1[B-](F)(F)[N+]1=C(C=CC1=C2)c1cccs1 |
PubChem CID | 90656230 |
ChEMBL Ligand | CHEMBL3261378 |
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PubChem CID | 90656230 |
BindingDB Ligand | 50013029 |
GPCRdb Ligand | MRS4162-BODIPY conjugate |
Ligand ID | 9469 |
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名称 | MRS4162-BODIPY conjugate |
别名 | BODIPY 630/650 conjugate 28 |
类别 | Synthetic organic |
学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
评价 |
MRS4162 is a BODIPY 630/650 conjugated P2Y6 receptor agonist that is useful as a molecular probe |
1. Jayasekara PS, Barrett MO, Ball CB, Brown KA, Hammes E, Balasubramanian R, Harden TK, Jacobson KA. (2014) 4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors.. J Med Chem, 57 (9): (3874-83). [PMID:24712832] |