首页
400-620-6333
切换导航
搜索
基本描述
| 英文名称 | HSD1590 |
|---|
名称和标识符
| INCHI | InChI=1S/C20H18BN3O3/c1-27-20-13(6-3-7-15(20)21(25)26)19-12-5-2-4-11(12)18-14-10-22-24-16(14)8-9-17(18)23-19/h3,6-10,25-26H,2,4-5H2,1H3,(H,22,24) |
|---|---|
| InChi Key | WTZMCUOBQPTERK-UHFFFAOYSA-N |
| Canonical SMILES | COc1c(cccc1B(O)O)c1nc2ccc3c(c2c2c1CCC2)cn[nH]3 |
| PubChem CID | 139030519 |
数据库链接
| PubChem CID | 139030519 |
|---|
关联配体
| Ligand ID | 10424 |
|---|---|
| 名称 | HSD1590 |
| 类别 | Synthetic organic |
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
| 生物活性评价 |
HSD1590 inhibits migration of MDA-MB-231 triple negative breast cancer cells in vitro, whereas netarsudil does not |
| 评价 |
HSD1590 is a boronic acid-containing Rho-associated kinase (ROCK) inhibitor |
产品问答
产品问答
参考文献
| 1. Dayal N, Mikek CG, Hernandez D, Naclerio GA, Yin Chu EF, Carter-Cooper BA, Lapidus RG, Sintim HO. (2019) Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors.. Eur J Med Chem, 180 (13): (449-456). [PMID:31330446] |
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）