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2,6-二异丙基苯酚

规格或纯度: 98%
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基本描述

规格或纯度 98%
英文名称 2,6-Diisopropylphenol
别名 丙泊酚；普鲁泊福；2,6-双(1-甲基乙基)苯酚
英文别名 propofol|2,6-DIISOPROPYLPHENOL|2078-54-8|Diprivan|Disoprofol|Disoprivan|Fresofol|Diisopropylphenol|Ampofol|2,6-Bis(1-methylethyl)phenol|Rapinovet|Propofolum|Phenol, 2,6-bis(1-methylethyl)-|Recofol|Ivofol|Pofol|Propofol-Lipuro|Diprifusor|Diprofol|Propovan|
储存温度 避光,充氩
运输条件 常规运输
产品介绍

该品是一种麻醉剂，也是麝香DDHI的中间体。

Product Introduction

2,6-Diisopropylphenol, a strongly hydrophobic substituted phenol, is a new intravenous anaesthetic. The antioxidant properties of 2,6-diisopropylphenol (Propofol) have been examined. It plays the role of an antioxidant by reacting with free radicals to form a phenoxyl radical, a property associated with all phenol-based free radical scavengers. 2,6-diisopropylphenol is an effective intravenous hypnotic agent, widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. It is useful for the induction and maintenance of general anaesthesia.


Application

2,6-Diisopropylphenol is suitable reagent used to study its effect on oxidative phosphorylation of isolated rat liver mitochondria. It is suitable reagent used in the preparation of bis(2,6-diisopropylphenoxy)bis(2-methyl-8-quinolinolato)titanium(IV) complex.

名称和标识符

EC号 218-206-6
IUPAC Name 2,6-di(propan-2-yl)phenol
INCHI InChI=1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChi Key OLBCVFGFOZPWHH-UHFFFAOYSA-N
Canonical SMILES CC(C)C1=C(C(=CC=C1)C(C)C)O
WGK Germany 3
RTECS SL0810000
PubChem CID 4943
UN Number 2810
分子量 178.27

化学和物理性质

溶解性 Very slightly soluble in water.
密度 0.962
敏感性 对空气敏感；对光敏感；对热敏感
凝固点 18 °C
折光率 1.514
闪点(℉) 235.4 °F
闪点(℃) 113 °C
沸点 256°C
熔点 18°C

安全和危险性（GHS）

象形图
ghs07

Harmful
信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H302: Harmful if swallowed
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319
WGK Germany 3
RTECS SL0810000
Merck Index 7834
个人防护装备 Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

关联配体

Ligand ID 5464
名称 propofol
别名 2,6-diisopropylphenol
类别 Synthetic organic
学名 2,6-bis(propan-2-yl)phenol
生物活性评价 As the GABAA binding site was reported to exist on both β3 homopentamers and α1β3 heteropentamers we have not tagged a primary drug target for propofol.
评价 Propofol is a short-acting (lasting 5-10 minutes) sedative.
Propofol is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).

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参考文献

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