Cas(6217-54-5), 顺式-4,7,10,13,16,19-二十二碳六烯酸(DHA)-阿拉丁试剂, 二十二烷六烯酸;DHA,Cervonic Acid,

货号 (SKU)	包装规格	是否现货
D100925-100mg	100mg	现货
D100925-500mg	500mg	现货
D100925-1g	1g	现货
D100925-5g	5g	现货

基本描述

规格或纯度	≥98%
英文名称	Cervonic Acid
别名	二十二烷六烯酸\|DHA
英文别名	Docosahexaenoic acid\|Doconexent\|Cervonic acid\|6217-54-5\|cis-4,7,10,13,16,19-Docosahexaenoic acid\|Docosahexaenoate\|Doconexentum\|Doconexento\|Doxonexent\|all-cis-DHA\|AquaGrow Advantage\|Martek DHA HM\|Ropufa 60\|(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hex
生化机理	内源性ω-3脂肪酸。作为一种选择性类视黄醇X受体（RXR）激动剂，其显示在RAR没有活动，甲状腺激素受体或维生素d受体（VDR）。激活所有三个RXR亚型。还显示在体外抑制Aβ1-42的纤颤和毒性。
储存温度	-20°C储存,充氩
运输条件	超低温冰袋运输
产品介绍	DHA是一种必需脂肪酸，其在神经组织中属最丰富的ω-3脂肪酸，特别是在视网膜和大脑。 DHA构成高达40％的视网膜和神经细胞膜的多不饱和脂肪酸总量池。使用鱼油DHA膳食补充剂，可抑制动脉粥样硬化和延误光感受器变性的视网膜色素变性的进度。新生儿的DHA不足会导致发育缺陷，大鼠DHA不足可能导致高血压。二十二碳六烯酸(DHA）是一种ω-3多不饱和脂肪酸，具有22个碳原子和6个双键，第一个双键发生的位点在三个位置的甲基末端（22点06的n-3）。 DHA是脂质膜和髓鞘的成分。 DHA也可作为信号分子的前体，如前列腺素和类二十烷酸。 DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes. Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa. Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats. Docosahexaenoic acid, DHA, is an omega-3 polyunsaturated fatty acid with 22 carbons and six double bonds, the first double bond occuring at position three from the methyl terminus (22:6 n-3). DHA is a component of lipid membranes and the myelin sheath. DHA also serves as a precursor for signaling molecules such as prostaglandins and eicosanoids.

名称和标识符

IUPAC Name	(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
INCHI	InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-
InChi Key	MBMBGCFOFBJSGT-KUBAVDMBSA-N
Canonical SMILES	CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)O
WGK Germany	3
PubChem CID	445580
分子量	328.49

数据库链接

PubChem CID	445580
ChEMBL Ligand	CHEMBL367149
Wikipedia	Docosahexaenoic_acid
ChEBI	CHEBI:28125
CAS Registry No.	6217-54-5
NURSA Ligand	10.1621/JKUDOZNM9G
RCSB PDB Ligand	HXA
DrugCentral Ligand	4289
GPCRdb Ligand	docosahexaenoic acid

化学和物理性质

溶解性	溶于DMSO, 最高浓度 (mg/mL): 32.85, 最高浓度(mM): 100；溶于ethanol, 最高浓度 (mg/mL): 32.85, 最高浓度(mM): 100
密度	0.94
敏感性	对空气、光线、热敏感
折光率	1.5049
闪点(℃)	62℃
熔点	-44.5--44.1°C

安全和危险性（GHS）

WGK Germany	3
Merck Index	3398

关联配体

Ligand ID	1051
名称	docosahexaenoic acid
别名	doconexent
类别	Metabolite
学名	(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
生物活性评价	Docosahexaenoic acid has been shown to inhibit amyloid β(1-42) fibril formation in vitro .
评价	Docosahexaenoic acid is an endogenous omega-3 fatty acid, activating all 3 retinoid X receptor isoforms. It has no activity at retinoic acid receptors (RARs), the thyroid hormone receptor or the vitamin D receptor (VDR).

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参考文献

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62. Ping K Yip,Amy L Bowes,Jodie C E Hall,Miguel A Burguillos,T H Richard Ip,Tracey Baskerville,Zhuo-Hao Liu,Moumin A E K Mohamed,Fanuelle Getachew,Anna D Lindsay,Saif-Ur-Rehman Najeeb,Phillip G Popovich,John V Priestley,Adina T Michael-Titus. (2019-04-12) Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury.. Human molecular genetics, 28 ((14)): (2427-2448). [PMID:30972415]
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91高清自产国产拍,无码免费A级毛片大全,日本欧美国产中文字幕,99re热视频这里只有精品视频首页

91高清自产国产拍,无码免费A级毛片大全,日本 欧美 国产中文字幕,99re热视频这里只有精品视频首页

顺式-4,7,10,13,16,19-二十二碳六烯酸(DHA)

库存信息

库存信息

库存信息

库存信息

基本描述

名称和标识符

数据库链接

化学和物理性质

安全和危险性（GHS）

关联配体

相关文档

质检报告COA

附件产品

产品问答

产品问答

参考文献

91高清自产国产拍,无码免费A级毛片大全,日本 欧美 国产中文字幕,99re热视频这里只有精品视频首页

91高清自产国产拍,无码免费A级毛片大全,日本欧美国产中文字幕,99re热视频这里只有精品视频首页

91高清自产国产拍,无码免费A级毛片大全,日本欧美国产中文字幕,99re热视频这里只有精品视频首页