英文名称 | BRL 37344 |
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别名 | BRL-37344;BRL37344 |
英文别名 | BRL-37344;BRL37344 |
IUPAC Name | 2-[4-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid |
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INCHI | InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 |
InChi Key | ZGGNJJJYUVRADP-ACJLOTCBSA-N |
Canonical SMILES | C[C@H](Cc1ccc(cc1)OCC(=O)O)NC[C@@H](c1cccc(c1)Cl)O |
PubChem CID | 9841972 |
PubChem CID | 9841972 |
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ChEMBL Ligand | CHEMBL284782 |
BindingDB Ligand | 50002133 |
CAS Registry No. | 116049-78-6 |
GPCRdb Ligand | BRL 37344 |
Ligand ID | 567 |
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名称 | BRL 37344 |
别名 | BRL37344 |
类别 | Synthetic organic |
学名 | 2-[4-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid |
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. |