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1,3-二[三(羟甲基)甲氨基]丙烷

具有宽缓冲范围的缓冲。
规格或纯度: 99%
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货号 (SKU) 包装规格 是否现货 价格 数量
B105640-5g
 5g 现货 Stock Image
B105640-25g
 25g 现货 Stock Image
B105640-100g
 100g 现货 Stock Image
B105640-500g
 500g 现货 Stock Image
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功能性连接子 双官能团连接子 生物缓冲液 脂肪链类化合物
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基本描述

规格或纯度 99%
英文名称 BIS-TRIS propane
别名 1,3-双[三(羟甲基)甲氨基]丙烷|BIS-TRIS丙烷|1,3-双[(三羟甲基)甲基氨基]丙烷|1,3-双[三(羟甲基)甲基胺]丙烷双-TRIS 丙烷
英文别名 64431-96-5|Bis-Tris propane|1,3-Bis[tris(hydroxymethyl)methylamino]propane|2,2'-(Propane-1,3-diylbis(azanediyl))bis(2-(hydroxymethyl)propane-1,3-diol)|2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL|1,3-Bis(tr
生化机理 在pH 6.3-9.5范围内有用的缓冲液。如此宽的缓冲范围是由于它的两个pKa值6.8（pKa1）和9.0（pKa2）如此之近。
应用 生物缓冲剂，用在生化诊断试剂盒、DNA/RNA提取试剂盒及PCR诊断试剂盒里。
储存温度 充氩
运输条件 常规运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

useful pH range 6.3 - 9.5 pKa (25 °C) (1) 6.8, (2) 9.0生物缓冲剂，用在生化诊断试剂盒、DNA/RNA提取试剂盒及PCR诊断试剂盒里。


应用：

BIS-TRIS丙烷可用于以下研究 作为研究具有不同亲核性质的阴离子对氧合肌红蛋白(MbO2)自动氧化影响的缓冲液。 来自硫化叶菌膜中葡萄糖结合蛋白的纯化。 作为GeO2矿化过程中的缓冲液。??

Bis-Tris Propane buffer, also known as BTP, is a zwitterionic biochemical buffer utilized for pH regulation in various laboratory applications, particularly in molecular biology, biochemistry, and electrophoresis. Its wide buffering range, spanning from pH 6.3 to 9.5, is attributed to its two pKa values of 6.8 (pKa1) and 9.0 (pKa2), which are close. This wide range makes it highly versatile for maintaining stable pH conditions in a variety of experiments. Furthermore, Bis-Tris Propane is a water-soluble buffer substance that plays a crucial role in enhancing the stability and activity of restriction enzymes. Specifically, its buffering capacity is advantageous for experiments that require pH levels as low as 6-7. When compared to Tris buffer, which has a poor buffering capacity below pH 7.5 and exhibits significant pKa fluctuations with temperature changes, Bis-Tris Propane proves to be a superior choice. Additionally, it finds application in conjunction with hydrochloric acid buffer to stabilize farnesyl diphosphate, particularly when isolated from Saccharomyces cerevisiae strains. Notably, it can also serve as a ligand, forming dinuclear hydroxo complexes with Lanthanides(III).


Product Application：
BIS-TRIS Propane may be used in the following studies: as a buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2). for purification of glucose-binding protein from membranes of Sulfolobus solfataricus. as a buffer during GeO2 mineralisation. as a buffer component in a study pertaining to environmental research as a buffer component to maintain optimal pH conditions during the purification and preparation of engineered enzymes

名称和标识符

EC号 264-899-3
IUPAC Name 2-[3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propylamino]-2-(hydroxymethyl)propane-1,3-diol
INCHI InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
InChi Key HHKZCCWKTZRCCL-UHFFFAOYSA-N
Canonical SMILES C(CNC(CO)(CO)CO)CNC(CO)(CO)CO
WGK Germany 3
PubChem CID 125132
分子量 282.33
Beilstein号 1786109
Reaxy-Rn 1786109

化学和物理性质

溶解性 Soluble in water
密度 1.326
敏感性 对湿度敏感
熔点 164-165°C

安全和危险性（GHS）

象形图
ghs07

Harmful
信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany 3
Reaxy-Rn 1786109
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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附件产品

  1. 1,3-二[三(羟甲基)甲氨基]丙烷
    1,3-二[三(羟甲基)甲氨基]丙烷, 98%, 5g

    ￥61.90

  2. N-三(羟甲基)甲氨基-2-羟基丙磺酸
    N-三(羟甲基)甲氨基-2-羟基丙磺酸, 99%, 25g

    ￥107.90

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参考文献

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