首页
400-620-6333
6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-(2-pyridin-2-ylethyl)imidazo[1,2-a]pyrimidine-2-carboxamide
- PubChem编号: 46900258
有货
切换导航
搜索
基本描述
| 英文名称 | 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-(2-pyridin-2-ylethyl)imidazo[1,2-a]pyrimidine-2-carboxamide |
|---|---|
| 别名 | compound 24dd |
| 英文别名 | compound 24dd |
名称和标识符
| IUPAC Name | 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-(2-pyridin-2-ylethyl)imidazo[1,2-a]pyrimidine-2-carboxamide |
|---|---|
| INCHI | InChI=1S/C22H20Cl2N6O/c1-13-17(11-25)20(16-6-5-14(23)10-18(16)24)30-12-19(29-22(30)28-13)21(31)27-9-7-15-4-2-3-8-26-15/h2-6,8,10,12H,7,9,11,25H2,1H3,(H,27,31) |
| InChi Key | JGJABGSOYWQCSC-UHFFFAOYSA-N |
| Canonical SMILES | NCc1c(C)nc2n(c1c1ccc(cc1Cl)Cl)cc(n2)C(=O)NCCc1ccccn1 |
| PubChem CID | 46900258 |
数据库链接
| PubChem CID | 46900258 |
|---|---|
| ChEMBL Ligand | CHEMBL1215376 |
关联配体
| Ligand ID | 8550 |
|---|---|
| 名称 | compound 24dd [PMID: 20684603] |
| 类别 | Synthetic organic |
| 学名 | 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-(2-pyridin-2-ylethyl)imidazo[1,2-a]pyrimidine-2-carboxamide |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 |
This compound is a selective inhibitor of dipeptidyl-peptidase 4 (DPP4) |
产品问答
产品问答
参考文献
| 1. Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y et al.. (2010) Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors.. J Med Chem, 53 (15): (5620-8). [PMID:20684603] |
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）