四氮唑溶液
规格或纯度:
用于DNA合成, 1 μm 滤膜过滤, ~0.45 M 乙腈溶液
- CAS编号: 288-94-8
- 分子式: CH2N4
- 分子量: 70.05
- Beilstein号: 105799
- MDL号: MFCD00005247
- PubChem编号: 67519
有货
规格或纯度 | 用于DNA合成, 1 μm 滤膜过滤, ~0.45 M 乙腈溶液 |
---|---|
英文名称 | Tetrazole solution |
别名 | 1H-四唑 |
英文别名 | 1H-Tetrazole;2H-tetrazole |
储存温度 | 室温 |
运输条件 | 常规运输 |
产品介绍 |
Tetrazole solution has been used as a catalyst for the preparation of phosphoramidite synthesis from stable dialkylaminophosphines as well as in the synthesis of phenothiazines. Tetrazole solution has been used as a catalyst for the preparation of phosphoramidite synthesis from stable dialkylaminophosphines as well as in the synthesis of phenothiazines. |
IUPAC Name | 2H-tetrazole |
---|---|
INCHI | InChI=1S/CH2N4/c1-2-4-5-3-1/h1H,(H,2,3,4,5) |
InChi Key | KJUGUADJHNHALS-UHFFFAOYSA-N |
Canonical SMILES | C1=NNN=N1 |
分子式 |
CH2N4 |
UN Number | 0504 |
PubChem CID | 67519 |
Beilstein号 | 105799 |
分子量 | 70.05 |
密度 | 0.798 |
---|---|
敏感性 | 对热和湿度敏感 |
沸点 | 84°C |
熔点 | ≥155°C |
闪点(℉) | 5 °C |
闪点(℃) | 5°C |
象形图 |
Oxidizing Explosive |
---|---|
信号词 | Danger |
危险声明 |
H272: May intensify fire; oxidizer H201: Explosive; mass explosion hazard |
预防措施声明 | P280,P370+P378,P210,P501,P240,P220,P370+P380,P230,P250,P372,P373,P401 |
WGK Germany | 3 |
个人防护装备 | Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter |
1. Konstantina C Fylaktakidou,Carolina D Duarte,Alexandros E Koumbis,Claude Nicolau,Jean-Marie Lehn. (2010-11-26) Polyphosphates and pyrophosphates of hexopyranoses as allosteric effectors of human hemoglobin: synthesis, molecular recognition, and effect on oxygen release.. ChemMedChem, 6 ((1)): (153-168). [PMID:21108295] |
2. Arturo Perez-Medrano,Diana L Donnelly-Roberts,Alan S Florjancic,Derek W Nelson,Tongmei Li,Marian T Namovic,Sridhar Peddi,Connie R Faltynek,Michael F Jarvis,William A Carroll. (2011-05-04) Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists.. Bioorganic & medicinal chemistry letters, 21 ((11)): (3297-3300). [PMID:21536435] |
3. Velladurai Rama,Kuppusamy Kanagaraj,Kasi Pitchumani. (2011-09-14) Syntheses of 5-substituted 1H-tetrazoles catalyzed by reusable CoY zeolite.. The Journal of organic chemistry, 76 ((21)): (9090-9095). [PMID:21910486] |
4. Yuko Yoshikawa,Seiji Komeda,Masako Uemura,Toshio Kanbe,Masahiko Chikuma,Kenichi Yoshikawa,Tadayuki Imanaka. (2011-10-19) Highly efficient DNA compaction mediated by an in vivo antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.. Inorganic chemistry, 50 ((22)): (11729-11735). [PMID:22004345] |
5. Peter A Jordan,Scott J Miller. (2012-02-10) An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer.. Angewandte Chemie (International ed. in English), 51 ((12)): (2907-2911). [PMID:22319027] |
6. Duncan J Wardrop,John P Komenda. (2012-03-01) Dehydrative fragmentation of 5-hydroxyalkyl-1H-tetrazoles: a mild route to alkylidenecarbenes.. Organic letters, 14 ((6)): (1548-1551). [PMID:22372676] |
7. Adina Morozan,Pascale Jégou,Mathieu Pinault,Stéphane Campidelli,Bruno Jousselme,Serge Palacin. (2012-03-06) Metal-free nitrogen-containing carbon nanotubes prepared from triazole and tetrazole derivatives show high electrocatalytic activity towards the oxygen reduction reaction in alkaline media.. ChemSusChem, 5 ((4)): (647-651). [PMID:22389330] |
8. Hamid Mofakham,Ahmad Shaabani,Sajjad Mousavifaraz,Fatemeh Hajishaabanha,Shabnam Shaabani,Seik Weng Ng. (2012-05-18) A novel one-pot pseudo-five-component condensation reaction towards bifunctional diazepine-tetrazole containing compounds: synthesis of 1H-tetrazolyl-1H-1,4-diazepine-2,3-dicarbonitriles and 1H-tetrazolyl-benzo[b][1,4]diazepines.. Molecular diversity, 16 ((2)): (351-356). [PMID:22592603] |
9. Nieves R Paz,Andrés G Santana,Cosme G Francisco,Ernesto Suárez,Concepción C González. (2012-06-15) Synthesis of tetrazole-fused glycosides by a tandem fragmentation-cyclization reaction.. Organic letters, 14 ((13)): (3388-3391). [PMID:22694091] |
10. Mohamad Sabbah,Fanny Fontaine,Lucie Grand,Mohamed Boukraa,Mohamed L Efrit,Alain Doutheau,Laurent Soulère,Yves Queneau. (2012-07-04) Synthesis and biological evaluation of new N-acyl-homoserine-lactone analogues, based on triazole and tetrazole scaffolds, acting as LuxR-dependent quorum sensing modulators.. Bioorganic & medicinal chemistry, 20 ((15)): (4727-4736). [PMID:22748707] |
11. Lauren M Tedaldi,Michael Pierce,Gerd K Wagner. (2012-11-14) Optimised chemical synthesis of 5-substituted UDP-sugars and their evaluation as glycosyltransferase inhibitors.. Carbohydrate research, 364 (): (22-27). [PMID:23147042] |
12. Ju-Ying Li,Xin-Qi Zhou,Yi Zhou,Yuan Fang,Cheng Yao. (2012-12-05) A highly specific tetrazole-based chemosensor for fluoride ion: a new sensing functional group based on intramolecular proton transfer.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102 (): (66-70). [PMID:23207417] |
13. Satsuki Otsuki,Shinichi Nishimura,Hisae Takabatake,Kozue Nakajima,Yasuaki Takasu,Toru Yagura,Yuki Sakai,Akira Hattori,Hideaki Kakeya. (2013-02-19) Chemical tagging of a drug target using 5-sulfonyl tetrazole.. Bioorganic & medicinal chemistry letters, 23 ((6)): (1608-1611). [PMID:23414805] |
14. Xiaobao Xu,Bingyan Zhang,Jin Cui,Dehua Xiong,Yan Shen,Wei Chen,Licheng Sun,Yibing Cheng,Mingkui Wang. (2013-07-19) Efficient p-type dye-sensitized solar cells based on disulfide/thiolate electrolytes.. Nanoscale, 5 ((17)): (7963-7969). [PMID:23863997] |
15. Olga I Shmatova,Valentine G Nenajdenko. (2013-08-16) Synthesis of tetrazole-derived organocatalysts via azido-Ugi reaction with cyclic ketimines.. The Journal of organic chemistry, 78 ((18)): (9214-9222). [PMID:23944996] |
16. Yann Garcia,N N Adarsh,Anil D Naik. (2013-08-16) Crystal engineering of Fe(II) spin crossover coordination polymers derived from triazole or tetrazole ligands.. Chimia, 67 ((6)): (411-418). [PMID:23945101] |
17. Ewa Radzikowska,Janina Baraniak. (2014-11-05) Synthesis of PS/PO-chimeric oligonucleotides using mixed oxathiaphospholane and phosphoramidite chemistry.. Organic & biomolecular chemistry, 13 ((1)): (269-276). [PMID:25363356] |
18. Govindasamy Balasubramani,Rajendiran Ramkumar,Narayanaswamy Krishnaveni,Annamalai Pazhanimuthu,Thillainathan Natarajan,Rajamani Sowmiya,Pachiappan Perumal. (2014-11-30) Structural characterization, antioxidant and anticancer properties of gold nanoparticles synthesized from leaf extract(decoction)of Antigonon leptopus Hook. &Arn.. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 30 (): (83-89). [PMID:25432487] |
19. Chun-Nun Chao,Yih-Leh Huang,Mien-Chun Lin,Chiung-Yao Fang,Cheng-Huang Shen,Pei-Lain Chen,Meilin Wang,Deching Chang,Chih-En Tseng. (2015-01-28) Inhibition of human diffuse large B-cell lymphoma growth by JC polyomavirus-like particles delivering a suicide gene.. Journal of translational medicine, 13 (): (29-29). [PMID:25623859] |
20. Baoling Chen,Wen Xu,Ran Pan,P Chen. (2015-06-10) Design and characterization of a new peptide vector for short interfering RNA delivery.. Journal of nanobiotechnology, 13 (): (39-39). [PMID:26054932] |
21. Mi Seon Kim,Yunmi Lee,Gi-Ho Sung,Ji Hye Kim,Jae Gwang Park,Han Gyung Kim,Kwang Soo Baek,Jae Han Cho,Jaegu Han,Kang-Hyo Lee,Sungyoul Hong,Jong-Hoon Kim,Jae Youl Cho. (2015-07-15) Pro-Apoptotic Activity of 4-Isopropyl-2-(1-Phenylethyl) Aniline Isolated from Cordyceps bassiana.. Biomolecules & therapeutics, 23 ((4)): (367-373). [PMID:26157554] |
22. Eline Bartolami,Yannick Bessin,Nadir Bettache,Magali Gary-Bobo,Marcel Garcia,Pascal Dumy,Sébastien Ulrich. (2015-08-08) Multivalent DNA recognition by self-assembled clusters: deciphering structural effects by fragments screening and evaluation as siRNA vectors.. Organic & biomolecular chemistry, 13 ((36)): (9427-9438). [PMID:26248061] |
23. Jun Ho Kim,Mi-Yeon Kim,Jong-Hoon Kim,Jae Youl Cho. (2015-09-04) Fisetin Suppresses Macrophage-Mediated Inflammatory Responses by Blockade of Src and Syk.. Biomolecules & therapeutics, 23 ((5)): (414-420). [PMID:26336580] |
24. A D Barone,J Y Tang,M H Caruthers. (1984-05-25) In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports.. Nucleic acids research, 12 ((10)): (4051-4061). [PMID:6728676] |
25. Michael Limbach. (2006-12-29) 5-(pyrrolidin-2-yl)-1H-tetrazole and 5-[(pyrrolidin-2-yl)methyl]-1H-tetrazole: proline surrogates with increased potential in asymmetric catalysis.. Chemistry & biodiversity, 3 ((2)): (119-133). [PMID:17193251] |
26. Salim Khiati,Nathalie Pierre,Soahary Andriamanarivo,Mark W Grinstaff,Nessim Arazam,Frédéric Nallet,Laurence Navailles,Philippe Barthélémy. (2009-08-29) Anionic nucleotide--lipids for in vitro DNA transfection.. Bioconjugate chemistry, 20 ((9)): (1765-1772). [PMID:19711898] |
27. Zhipeng Yu,Lok Yin Ho,Qing Lin. (2011-07-09) Rapid, photoactivatable turn-on fluorescent probes based on an intramolecular photoclick reaction.. Journal of the American Chemical Society, 133 ((31)): (11912-11915). [PMID:21736329] |
28. Xiao-Yang He,Peng Zou,Jiayin Qiu,Ling Hou,Shibo Jiang,Shuwen Liu,Lan Xie. (2011-10-22) Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors.. Bioorganic & medicinal chemistry, 19 ((22)): (6726-6734). [PMID:22014749] |
29. Silvia Bezer,Srinivas Rapireddy,Yury A Skorik,Danith H Ly,Catalina Achim. (2011-11-09) Coordination-driven inversion of handedness in ligand-modified PNA.. Inorganic chemistry, 50 ((23)): (11929-11937). [PMID:22059624] |
30. Frank H Allen,Colin R Groom,John W Liebeschuetz,David A Bardwell,Tjelvar S G Olsson,Peter A Wood. (2012-02-07) The hydrogen bond environments of 1H-tetrazole and tetrazolate rings: the structural basis for tetrazole-carboxylic acid bioisosterism.. Journal of chemical information and modeling, 52 ((3)): (857-866). [PMID:22303876] |
31. Falgun Shah,Jiri Gut,Jennifer Legac,Devleena Shivakumar,Woody Sherman,Philip J Rosenthal,Mitchell A Avery. (2012-02-16) Computer-aided drug design of falcipain inhibitors: virtual screening, structure-activity relationships, hydration site thermodynamics, and reactivity analysis.. Journal of chemical information and modeling, 52 ((3)): (696-710). [PMID:22332946] |
32. Gopalakrishnan Aridoss,Chunqing Zhao,Gabriela L Borosky,Kenneth K Laali. (2012-04-07) Experimental and GIAO 15N NMR study of substituent effects in 1H-tetrazoles.. The Journal of organic chemistry, 77 ((8)): (4152-4155). [PMID:22480162] |
33. Gaston H Vondenhoff,Bharat Gadakh,Konstantin Severinov,Arthur Van Aerschot. (2012-08-01) Microcin C and albomycin analogues with aryl-tetrazole substituents as nucleobase isosters are selective inhibitors of bacterial aminoacyl tRNA synthetases but lack efficient uptake.. Chembiochem : a European journal of chemical biology, 13 ((13)): (1959-1969). [PMID:22847961] |
34. Rafie H Abu-Eittah,Khaled E El-Kelany. (2012-10-06) A theoretical DFT study on the structural parameters and azide-tetrazole equilibrium in substituted azidothiazole systems.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99 (): (316-328). [PMID:23036938] |
35. Marouan Rami,Elodie Landagaray,Mohamed Ettaoussi,Koussayla Boukhalfa,Daniel-Henri Caignard,Philippe Delagrange,Pascal Berthelot,Sa?d Yous. (2012-12-25) Novel conformationally constrained analogues of agomelatine as new melatoninergic ligands.. Molecules (Basel, Switzerland), 18 ((1)): (154-166). [PMID:23262445] |
36. Anh Thu Nguyen-Trung,Denis Tritsch,Catherine Grosdemange-Billiard,Michel Rohmer. (2013-02-19) Synthesis of tetrazole analogues of phosphonohydroxamic acids: an attempt to improve the inhibitory activity against the DXR.. Bioorganic & medicinal chemistry letters, 23 ((6)): (1643-1647). [PMID:23414808] |
37. Katia Jedeon,Sophia Loiodice,Clémence Marciano,Alexia Vinel,Marie-Chantal Canivenc Lavier,Ariane Berdal,Sylvie Babajko. (2014-07-09) Estrogen and bisphenol A affect male rat enamel formation and promote ameloblast proliferation.. Endocrinology, 155 ((9)): (3365-3375). [PMID:25004094] |
38. M A Costa,E Keating,B M Fonseca,N A Teixeira,G Correia-da-Silva. (2014-09-10) 2-Arachidonoylglycerol impairs human cytotrophoblast cells syncytialization: influence of endocannabinoid signalling in placental development.. Molecular and cellular endocrinology, 399 (): (386-394). [PMID:25199616] |
39. Roosmarijn E Vandenbroucke,Claude Libert. (2014-11-08) Is there new hope for therapeutic matrix metalloproteinase inhibition?. Nature reviews. Drug discovery, 13 ((12)): (904-927). [PMID:25376097] |