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（±）-α-烟酸生育酚

规格或纯度: 98%
有货

库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
T118723-5g 5g 现货 Stock Image
T118723-25g 25g 现货 Stock Image
T118723-100g 100g 现货 Stock Image
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基本描述

规格或纯度 98%
英文名称 (±)-α-Tocopherol nicotinate
别名 生育酚烟酸酯
英文别名 Vitamin E nicotinate 3,4-dihydro-2,5,7,8-tetramehyl- 2(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R(4R,8R)]3-Pyridnecarboxyic acid
储存温度 2-8°C储存
运输条件 冰袋运输

名称和标识符

EC号 257-501-4
IUPAC Name [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] pyridine-3-carboxylate
INCHI InChI=1S/C35H53NO3/c1-24(2)13-9-14-25(3)15-10-16-26(4)17-11-20-35(8)21-19-31-29(7)32(27(5)28(6)33(31)39-35)38-34(37)30-18-12-22-36-23-30/h12,18,22-26H,9-11,13-17,19-21H2,1-8H3/t25-,26-,35-/m1/s1
InChi Key MSCCTZZBYHQMQJ-AZAGJHQNSA-N
Canonical SMILES CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C3=CN=CC=C3)C
分子式

C35H53NO3
PubChem CID 27990
分子量 535.8

安全信息

WGK Germany 3
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

参考文献

1. Y Hata,A Terashi,T Matsuzaki,E Ohtomo,Y Goto.  (1992-01-01)  A prevention trial on cerebral infarction with dl-alpha-tocopheryl nicotinate--rationales for trial. The Alpha-Tocopheryl Nicotinate Prevention Study Group..  Journal of nutritional science and vitaminology,    ():  (204-207).  [PMID:1297741]
2. H P Wu,T Y Tai,L M Chuang,B J Lin,J D Wang,C M Teng.  (1992-03-01)  Effect of tocopherol on platelet aggregation in non-insulin-dependent diabetes mellitus: ex vivo and in vitro studies..  Journal of the Formosan Medical Association = Taiwan yi zhi,  91  ((3)):  (270-275).  [PMID:1354687]
3. N Hidiroglou,L R McDowell,A M Papas,M Antapli,N S Wilkinson.  (1992-08-01)  Bioavailability of vitamin E compounds in lambs..  Journal of animal science,  70  ((8)):  (2556-2561).  [PMID:1506317]
4. Y Ihara,K Nobukuni,R Namba,K Kamisaka,M Kibata,K Kajinami,H Fujita,H Mabuchi,T Shirabe,K Ohshima.  (1991-11-01)  A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate..  Journal of the neurological sciences,  106  ((1)):  (10-18).  [PMID:1779233]
5. A Noma,S Maeda,M Okuno,A Abe,Y Muto.  (1990-10-01)  Reduction of serum lipoprotein(a) levels in hyperlipidaemic patients with alpha-tocopheryl nicotinate..  Atherosclerosis,  84  ((2-3)):  (213-217).  [PMID:2149270]
6. T Koyama,T Araiso.  (1988-10-01)  Effects of alpha-tocopherol-nicotinate administration on the microdynamics of phospholipids of erythrocyte membranes in human subjects..  Journal of nutritional science and vitaminology,  34  ((5)):  (449-457).  [PMID:3230416]
7. A Funakoshi,T Kimura,H Shinozaki,H Ibayashi.  (1986-04-01)  Comparisons between absorption of vitamin E in patients with chronic pancreatitis and healthy controls: the bioavailability of vitamin E..  The Tohoku journal of experimental medicine,  148  ((4)):  (393-401).  [PMID:3738905]
8. N Inagaki,H Nagai,A Koda.  (1984-01-01)  Effect of vitamin E on IgE antibody formation in mice..  Journal of pharmacobio-dynamics,  7  ((1)):  (70-74).  [PMID:6726616]
9. N Suzuki,T Nakamura.  (1983-04-01)  Metabolism of the nicotinic acid moiety of d,l-alpha-tocopheryl nicotinate..  Journal of nutritional science and vitaminology,  29  ((2)):  (93-103).  [PMID:6886843]
10. H Yuasa,D Asahi,Y Takashima,Y Kanaya,K Shinozawa.  (1994-11-01)  Application of calcium silicate for medicinal preparation. I. Solid preparation adsorbing an oily medicine to calcium silicate..  Chemical & pharmaceutical bulletin,  42  ((11)):  (2327-2331).  [PMID:7859331]
11. N Hidiroglou,M S Wolynetz,L R McDowell,A M Papas,M Antapli,N S Wilkinson.  (1993-01-01)  Serum total cholesterol, high-density lipoprotein-cholesterol and triglyceride concentrations in lambs following supplementation with various forms of tocopherol..  Reproduction, nutrition, development,  33  ((3)):  (263-268).  [PMID:8216754]
12. Y Takashima,H Yuasa,Y Kanaya,I Nomura,K Shinozawa.  (1999-09-30)  Reduction of tablet coloration at tableting for oily medicine (tocopheryl nicotinate)..  International journal of pharmaceutics,  187  ((1)):  (125-135).  [PMID:10502619]
13. Y Ichitani,H Okaichi,T Yoshikawa,Y Ibata.  (1992-11-15)  Learning behaviour in chronic vitamin E-deficient and -supplemented rats: radial arm maze learning and passive avoidance response..  Behavioural brain research,  51  ((2)):  (157-164).  [PMID:1466782]
14. A Baruffini,E De Lorenzi,C Gandini,M Kitsos,G Massolini.  (1992-02-28)  High-performance liquid chromatographic determination of alpha-tocopheryl nicotinate in cosmetic preparations..  Journal of chromatography,  593  ((1-2)):  (95-97).  [PMID:1639917]
15. M Hidiroglou,E Charmley.  (1991-04-01)  Comparative studies on bioavailability and tissue uptake of two intraruminally or intraperitoneally administered esters of alpha-tocopherol in sheep..  American journal of veterinary research,  52  ((4)):  (640-642).  [PMID:2053738]
16. H Tanaka,M Mino,T Takeuchi.  (1988-06-01)  A nutritional evaluation of vitamin E status in very low birth weight infants with respect to changes in plasma and red blood cell tocopherol levels..  Journal of nutritional science and vitaminology,  34  ((3)):  (293-307).  [PMID:3183778]
17. P Schlieper,H Tawfik.  (1987-08-01)  Antiarrhythmic activity of alpha-tocopherol nicotinate and related compounds and their physico-chemical properties..  Arzneimittel-Forschung,  37  ((8)):  (920-923).  [PMID:3675687]
18. K N Prasad,J Edwards-Prasad.  (1982-02-01)  Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture..  Cancer research,  42  ((2)):  (550-555).  [PMID:6275980]
19. K Ikeda,T Hikima,K Kusunoki,Y Watanabe,M Ohara,H Fujihashi,T Shimojima,Y Kurihashi,K Maekawa,T Shimojima,Y Kurihashi.  (1982-12-01)  [Clinical effect of dentifrice containing dl-alpha-Tocopheryl nicotinate]..  Nihon Shishubyo Gakkai kaishi,  24  ((4)):  (619-632).  [PMID:6963312]
20. J Hasegawa,Y Tomono,T Fujita,K Sugiyama,K Hamamura.  (1981-05-01)  The effect of food on the absorption of alpha-tocopheryl nicotinate in beagle dogs and human volunteers..  International journal of clinical pharmacology, therapy, and toxicology,  19  ((5)):  (216-219).  [PMID:7251237]
21. T W Chung,J J Yu,D Z Liu.  (1998-06-03)  Reducing lipid peroxidation stress of erythrocyte membrane by alpha-tocopherol nicotinate plays an important role in improving blood rheological properties in type 2 diabetic patients with retinopathy..  Diabetic medicine : a journal of the British Diabetic Association,  15  ((5)):  (380-385).  [PMID:9609359]
22. Yasuhiro Okamoto,Magobei Yamamoto,Hatsumi Aki.  (2002-09-19)  [Enhancing effects of ion-pair complexes on skin permeation of cromolyn in vitro]..  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,  122  ((9)):  (673-679).  [PMID:12235858]
23. Haruko Oshima,Kaori Tsuji,Tsunao Oh-I,Michiyuki Koda.  (2003-05-21)  Allergic contact dermatitis due to DL-alpha-tocopheryl nicotinate..  Contact dermatitis,  48  ((3)):  (167-168).  [PMID:12755738]
24. Lucia Marcocci,Yuichiro J Suzuki.  (2019-05-15)  Metabolomics Studies to Assess Biological Functions of Vitamin E Nicotinate..  Antioxidants (Basel, Switzerland),  8  ((5)):  ().  [PMID:31083512]

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