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(2'S)-2'-脱氧-2'-氟-5-乙炔基尿苷, (F-ara-EdU)
规格或纯度:
试剂级
- CAS编号: 95740-26-4
- 分子式: C11H11FN2O5
- 分子量: 270.21
- MDL号: MFCD22417248
- PubChem编号: 514810
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基本描述
| 规格或纯度 | 试剂级 |
|---|---|
| 英文名称 | (2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine, (F-ara-EdU) |
| 产品介绍 |
应用 一种比 EdU 和 BrdU 毒性都低的体内 DNA 合成探针。当需要延长细胞存活和未受干扰的细胞周期进展时，非常适合用于代谢 DNA 标记。 Description A probe for DNA synthesis in vivo that is less toxic than both EdU and BrdU. Ideally suited for metabolic DNA labeling when prolonged cell survival and undisturbed cell cycle progression are required. |
名称和标识符
| IUPAC Name | 5-ethynyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| INCHI | InChI=1S/C11H11FN2O5/c1-2-5-3-14(11(18)13-9(5)17)10-7(12)8(16)6(4-15)19-10/h1,3,6-8,10,15-16H,4H2,(H,13,17,18)/t6-,7+,8-,10-/m1/s1 |
| InChi Key | YEEGMPUOCRQFRV-IBCQBUCCSA-N |
| Canonical SMILES | C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F |
| 分子式 |
C11H11FN2O5 |
| PubChem CID | 514810 |
| 分子量 | 270.21 |
参考文献
| 1. Anne B Neef, Nathan W Luedtke,. (2011-12-07) Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides.. Proceedings of the National Academy of Sciences of the United States of America, 108 ((51)): ( 20404-20409 ). [PMID:22143759] |
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