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FSH β subunit

有货

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
rp174043-500μg	500μg	期货
rp174043-1mg	1mg	期货

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基本描述

产品名称	FSH β subunit

产品规格参数

CAS编号和信息	rp174043

数据库链接

Wikipedia	FSHB
CATH/Gene3D	2.10.90.10

关联配体

Ligand ID

3733

名称

FSH β subunit

别名

follitropin beta subunit

类别

Peptide

学名

4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

生物活性评价

The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).

评价

Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth.

配体家族

Glycoprotein hormones

基因/前体

Gene symbol	Gene name	Precursor protein name	Species	别名
FSHB	follicle stimulating hormone subunit beta	follitropin subunit beta precursor	Human	follitropin, beta chain, follicle-stimulating hormone beta subunit, follicle stimulating hormone, beta polypeptide, follicle stimulating hormone beta subunit

单字母多肽序列

NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE

三字母多肽序列

Asn-Ser-Cys-Glu-Leu-Thr-Asn-Ile-Thr-Ile-Ala-Ile-Glu-Lys-Glu-Glu-Cys-Arg-Phe-Cys-Ile-Ser-Ile-Asn-Thr-Thr-Trp-Cys-Ala-Gly-Tyr-Cys-Tyr-Thr-Arg-Asp-Leu-Val-Tyr-Lys-Asp-Pro-Ala-Arg-Pro-Lys-Ile-Gln-Lys-Thr-Cys-Thr-Phe-Lys-Glu-Leu-Val-Tyr-Glu-Thr-Val-Arg-Val-Pro-Gly-Cys-Ala-His-His-Ala-Asp-Ser-Leu-Tyr-Thr-Tyr-Pro-Val-Ala-Thr-Gln-Cys-His-Cys-Gly-Lys-Cys-Asp-Ser-Asp-Ser-Thr-Asp-Cys-Thr-Val-Arg-Gly-Leu-Gly-Pro-Ser-Tyr-Cys-Ser-Phe-Gly-Glu-Met-Lys-Glu

翻译后修饰

The production of biologically active FSH requires appropriately folded and glycosylated FSHβ and common α subunits that assemble to form the heterodimeric hormone. FSHβ is glysolyated at asparagines 7 and 24, while the common α subunit is glycosylated at asparagines 52 and 78. They then assemble to form the biologically active FSH heterodimer .

化学修饰

参考文献

1. Bousfield GR, Dias JA. (2011) Synthesis and secretion of gonadotropins including structure-function correlates.. Rev Endocr Metab Disord, 12 (4): (289-302). [PMID:21739108]