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基本描述
| 产品名称 | C4a |
|---|
产品规格参数
| CAS编号和信息 | rp173610 |
|---|
数据库链接
| UniProtKB | P0C0L4 |
|---|---|
| Ensembl Gene | ENSG00000227746 |
| Entrez Gene | 720 |
| Wikipedia | C4a |
| DrugBank Target | P0C0L4 |
| CATH/Gene3D | 1.20.91.20, 2.60.40.10, 2.60.40.690 |
关联配体
| Ligand ID | 6547 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 名称 | C4a | ||||||||||
| 别名 | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 | ||||||||||
| 类别 | Peptide | ||||||||||
| 学名 | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. | ||||||||||
| 配体家族 | Complement components and ligands | ||||||||||
| 基因/前体 |
|
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| 单字母多肽序列 | NVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQR | ||||||||||
| 三字母多肽序列 | Asn-Val-Asn-Phe-Gln-Lys-Ala-Ile-Asn-Glu-Lys-Leu-Gly-Gln-Tyr-Ala-Ser-Pro-Thr-Ala-Lys-Arg-Cys-Cys-Gln-Asp-Gly-Val-Thr-Arg-Leu-Pro-Met-Met-Arg-Ser-Cys-Glu-Gln-Arg-Ala-Ala-Arg-Val-Gln-Gln-Pro-Asp-Cys-Arg-Glu-Pro-Phe-Leu-Ser-Cys-Cys-Gln-Phe-Ala-Glu-Ser-Leu-Arg-Lys-Lys-Ser-Arg-Asp-Lys-Gly-Gln-Ala-Gly-Leu-Gln-Arg | ||||||||||
| 翻译后修饰 | Predicted disulphide bond formation between cysteine residues at positions 22 and 48, 23 and 55, and 36 and 56. | ||||||||||
| 化学修饰 |
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产品问答
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