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Recombinant Human IFN-alpha-2B Protein(Active)

规格或纯度: Animal Free, >98% ( SDS-PAGE and HPLC), Active, Yeast, No tag, 24-188 aa
  • 蛋白长度: Full length protein
  • 蛋白标签: No tag

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货号 (SKU) 包装规格 是否现货 价格 数量
rp156087-10μg 10μg 现货 Stock Image
rp156087-100μg 100μg 现货 Stock Image
rp156087-1mg 1mg 期货 Stock Image
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基本描述

产品名称 Recombinant Human IFN-alpha-2B Protein
规格或纯度 Animal Free, >98% ( SDS-PAGE and HPLC), Active, Yeast, No tag, 24-188 aa
产品介绍

产品描述：

干扰素（IFN）以其在宿主防御机制中的关键作用而闻名。Ⅰ型干扰素包括IFN-alpha 家族，IFN-beta， -omega，-kappa 和 Limitin/IFN-zeta，对调节病毒感染的免疫应答具有重要意义。Ⅱ型干扰素组仅包括干扰素γ。IFN-γ是一种多功能细胞因子，具有抗增殖、免疫调节和促炎症作用，对免疫应答的许多方面都很重要。Ⅲ型干扰素家族包括IL-29/IFN-lambda 1， IL-28A/IFN-lambda 2， IL-28B/IFN-lambda 3， and IFN-lambda 4。与Ⅰ型干扰素类似，Ⅲ型干扰素具有抗病毒、抗增殖和免疫调节作用。

IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
生物活性 Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.6 × 10^8 IU/mg.
种属 Human
氨基酸 24-188 aa
序列 CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
蛋白标签 No tag
蛋白长度 Full length protein
Carrier Free Yes
AnimalFree Yes
Accession# P01563
来源 Recombinant
预测分子量 19.3 kDa

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 μm filtered solution in 1×PBS, pH 7.4, with 0.02 % Tween-20.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Upon delivery aliquot, Store at -20°C, Avoid freeze / thaw cycles. Lyophilized with no additives. This product is an active protein and may elicit a biological response in vivo, handle with caution.

图片

Recombinant Human IFN-alpha-2B Protein (rp156087)-Protein Bioactivity
Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.6×10??IU/mg.

Recombinant Human IFN-alpha-2B Protein (rp156087)-SDS-PAGE
Recombinant Human IFN-alpha-2B Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie? Blue staining. Showing a single band at 19.3?kDa under reducing conditions and 16.2?kDa under non-reducing conditions.

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