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Recombinant Human TNFRSF1A Protein(Active)

功能和特点
  • 规格或纯度: Animal Free, >97%(SDS-PAGE, HPLC), Active, E.coli, No tag, 22-211 aa
  • 生物活性: Fully biologically active when compared to standard. The ED?? as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.
  • 蛋白标签: No tag
  • 应用: Active, SDS-PAGE
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp152513-10μg (试用装)
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10μg 现货 Stock Image
rp152513-50μg
50μg 现货 Stock Image
rp152513-100μg
100μg 现货 Stock Image
rp152513-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human TNFRSF1A Protein
规格或纯度 Animal Free, >97%(SDS-PAGE, HPLC), Active, E.coli, No tag, 22-211 aa
产品介绍


Purity

> 97 % by SDS-PAGE and HPLC analyses.


Function

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

生物活性 Fully biologically active when compared to standard. The ED?? as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.
种属 Human
氨基酸 22-211 aa
序列 IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT
纯度 >97%(SDS-PAGE, HPLC)
蛋白标签 No tag
蛋白长度 Protein fragment
无载体 Yes
无动物源 Yes
Accession # P19438
来源 Recombinant
预测分子量 21.2 kDa

产品规格参数

应用 Active, SDS-PAGE
物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 ℃ as supplied. - 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. - 3 months, -20 to -70 ℃ under sterile conditions after reco

图片

Recombinant Human TNFRSF1A Protein (rp152513)-Protein Bioactivity
Fully biologically active when compared to standard. The ED???as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/mL, corresponding to a specific activity of > 2 × 104 IU/mg in the presence of 0.25 ng/mL of rHuTNF-alpha.

Recombinant Human TNFRSF1A Protein (rp152513)-SDS-PAGE
Recombinant Human TNFRSF1A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie? Blue staining. Showing a single band at 21.2?kDa under reducing conditions and 19.0?kDa under non-reducing conditions.

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