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Recombinant Human IL-17RA/IL-17R Protein(Active)

Recombinant human IL-17RA Receptor protein (Active)
规格或纯度: Animal Free,>95%(SDS-PAGE), Active, 293F, Fc&His, 33-320aa
  • 纯度: >95%(SDS-PAGE)
  • 蛋白标签: Fc, 6×His tag at the C-terminus

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp147441-10μg 10μg 期货 Stock Image
rp147441-50μg 50μg 期货 Stock Image
rp147441-100μg 100μg 期货 Stock Image
rp147441-1mg 1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-17RA/IL-17R Protein
规格或纯度 Animal Free,>95%(SDS-PAGE), Active, 293F, Fc&His, 33-320aa
产品介绍


Purity

>95% SDS-PAGE


Function

Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.


种属 Human
氨基酸 33 to 320 aa
序列 LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFF
蛋白标签 Fc, 6×His tag at the C-terminus
Accession# Q96F46
预测分子量 60 kDa

产品规格参数

物理外观 Lyophilized
储存缓冲液 PBS(PH7.4), containing 5% trehalose, 5% mannitol
复溶 Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
储存温度 -20°C储存
运输条件 冰袋运输
稳定性与储存 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

图片

Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Protein Bioactivity
Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED?? for this effect is 0.08 μg/mL in the presence of 10 ng/mL recombinant human IL-17.

Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Binding ELISA
IL-17RA/IL-17R Protein (rp147441) was serially diluted 3-fold and coated on a Clear Polystyrene Microplate (W291037) can bind Brodalumab (anti-IL17RA) (Ab169276). The EC?? for this effect is 5.5 ng/mL.

Recombinant Human IL-17RA/IL-17R Protein (rp147441) - SDS-PAGE
2 μg/lane of Recombinant Human IL-17RA/IL-17R was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie? Blue staining, showing a band at 91.3 kDa under reducing conditions and 208.1 kDa under non-reducing conditions.

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