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Recombinant Human IL-17F Protein(Active)

规格或纯度: Animal Free, >95%(SDS-PAGE, HPLC), Active, E.coli, No tag, 31-163 aa
  • 蛋白长度: Full length protein
  • 蛋白标签: No tag

  • 应用: Cell Culture,Active
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp147435-10μg 10μg 现货 Stock Image
rp147435-50μg 50μg 现货 Stock Image
rp147435-100μg 100μg 现货 Stock Image
rp147435-1mg 1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-17F Protein
规格或纯度 Animal Free, >95%(SDS-PAGE, HPLC), Active, E.coli, No tag, 31-163 aa
产品介绍


Purity
>95% by SDS-PAGE and HPLC analyses.

Function
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.

生物活性 Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.
种属 Human
氨基酸 31-163 aa
序列 MRKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
蛋白标签 No tag
蛋白长度 Full length protein
Carrier Free Yes
AnimalFree Yes
Accession# Q96PD4
来源 Recombinant
预测分子量 30.1 kDa
SDS-PAGE 16.4 kDa, under reducing conditions.

产品规格参数

应用 Cell Culture,Active
物理外观 Lyophilized
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 6 mM HCl to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further d
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconst

图片

Recombinant Human IL-17F Protein (rp147435)-Protein Bioactivity
Fully biologically active when compared to standard. The ED???as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/mL, corresponding to a specific activity of > 5.0 × 10??IU/mg.


Recombinant Human IL-17F Protein (rp147435)-SDS-PAGE
Recombinant Human IL-17F Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie? Blue staining. Showing a single band at 16.4?kDa.

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