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Recombinant Human CXCL7/PBP Protein(Active)

规格或纯度: Animal Free, >97%( SDS-PAGE and HPLC), Active, E.coli, No tag, 59-128 aa
  • 蛋白长度: Protein fragment
  • 蛋白标签: No tag

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货号 (SKU) 包装规格 是否现货 价格 数量
rp144868-10μg 10μg 现货 Stock Image
rp144868-50μg 50μg 现货 Stock Image
rp144868-100μg 100μg 现货 Stock Image
rp144868-1mg 1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human CXCL7/PBP Protein
规格或纯度 Animal Free, >97%( SDS-PAGE and HPLC), Active, E.coli, No tag, 59-128 aa
产品介绍


Purity
>97% SDS-PAGE and HPLC analyses..

Function
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

Post-translational
Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)). Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor. NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils. NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.

生物活性 Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 1.0-10.0 ng/ml.
种属 Human
氨基酸 59-128 aa
序列 AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
蛋白标签 No tag
蛋白长度 Protein fragment
Carrier Free Yes
AnimalFree Yes
Accession# P02775
来源 Recombinant
预测分子量 7.6 kDa
SDS-PAGE 7.6 kDa

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PBS, pH 7.4, 50mM NaCl.
复溶 Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
储存温度 -20°C储存
运输条件 超低温冰袋运输
稳定性与储存 Upon delivery aliquot, Store at -20°C, Avoid freeze/thaw cycles. This product is an active protein and may elicit a biological response in vivo, handle with caution.

图片

Recombinant Human CXCL7/PBP Protein (rp144868)-Protein Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 1.0-10.0 ng/mL.

Recombinant Human CXCL7/PBP Protein (rp144868)-SDS-PAGE
Recombinant Human CXCL7/PBP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie? Blue staining, showing a band at 7.6 kDa under reducing conditions and 9.2-14.4?kDa under non-reducing conditions.

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