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Recombinant Human CCL4/MIP-1 beta Protein(Active)

规格或纯度: Animal Free, >96%(SDS-PAGE, HPLC), Active, E.coli, No tag, 24-92 aa
  • 蛋白长度: Full length protein
  • 蛋白标签: No tag

  • 应用: Active, SDS-PAGE
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp143746-10μg 10μg 现货 Stock Image
rp143746-50μg 50μg 现货 Stock Image
rp143746-100μg 100μg 现货 Stock Image
rp143746-1mg 1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human CCL4/MIP-1 beta Protein
规格或纯度 Animal Free, >96%(SDS-PAGE, HPLC), Active, E.coli, No tag, 24-92 aa
产品介绍


Purity

> 96 % by SDS-PAGE and HPLC analyses.


Function

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.



生物活性 Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/ml.
种属 Human
氨基酸 24-92 aa
序列 APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
蛋白标签 No tag
蛋白长度 Full length protein
Carrier Free Yes
AnimalFree Yes
Accession# P13236
来源 Recombinant
预测分子量 7.8 kDa

产品规格参数

应用 Active, SDS-PAGE
物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitu

图片

Protein Bioactivity-Recombinant Human CCL4/MIP-1 beta Protein (rp143746)-Protein Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/mL.

Recombinant Human CCL4/MIP-1 beta Protein (rp143746)-SDS-PAGE
Recombinant Human CCL4/MIP-1 beta Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie? Blue staining, showing a band at 7.8 kDa.

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