| 规格或纯度 | 10mM in DMSO |
|---|---|
| 英文名称 | Paeonol |
| 英文别名 | Peonol;1-(2-hydroxy-4-methoxyphenyl)ethanone |
| 生化机理 | Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM. |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
Information Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM. Paeonol (Peonol) is a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum. It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively. Paeonol shows antimutagenic, anti-inflammatory and analgesic effects. Paeonol also inhibits anaphylactic reaction by regulating histamine and TNF-α. In?vivo LD50: Mice 608-899mg/kg (i.p.). cell?lines： Concentrations： Incubation?Time： Powder?Purity:≥99% Information Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM. Paeonol (Peonol) is a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum. It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively. Paeonol shows antimutagenic, anti-inflammatory and analgesic effects. Paeonol also inhibits anaphylactic reaction by regulating histamine and TNF-α. In?vivo LD50: Mice 608-899mg/kg (i.p.). cell?lines： Concentrations： Incubation?Time： Powder?Purity:≥99% |
| IC50 | MAO-B, IC50: 42.5 μM |
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| Canonical SMILES | COC1=CC(=C(C=C1)C(C)=O)O |
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| 分子式 |
C9H10O3 |
| 分子量 | 166.17 |
| 溶解性 | Solubility (25°C) In vitro DMSO: 70 mg/mL (200.93 mM); Water: 70 mg/mL (200.93 mM); Ethanol: Insoluble; |
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