| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P187973-250mg | 250mg |
现货  |
| |
| P187973-1g | 1g |
现货 |
| |
| P187973-5g | 5g |
现货 |
|
| 规格或纯度 | 95% |
|---|---|
| 英文名称 | Primaquine |
| 别名 | N-(6-甲氧基喹啉-8-基)戊-1,4-二胺 |
| 英文别名 | Primaquine;8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline; N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine;N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| IUPAC Name | 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine |
|---|---|
| INCHI | InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3 |
| InChi Key | INDBQLZJXZLFIT-UHFFFAOYSA-N |
| Canonical SMILES | CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2 |
| 分子式 |
C15H21N3O |
| PubChem CID | 4908 |
| 分子量 | 259.4 |
| PubChem CID | 4908 |
|---|---|
| ChEMBL Ligand | CHEMBL506 |
| CAS Registry No. | 90-34-6 |
| Wikipedia | Primaquine |
| ChEBI | CHEBI:8405 |
| RCSB PDB Ligand | 1PQ |
| DrugCentral Ligand | 2266 |
| Ligand ID | 9952 |
|---|---|
| 名称 | primaquine |
| 类别 | Synthetic organic |
| 学名 | N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 |
Primaquine is a synthetic, 8-aminoquinoline derivative that has potent antimalarial activity. The approved drug is a racemic mixture and we show the chemical structure without stereochemistry to represent the mixture. The non-isomeric structure is also represented in the PubChem, ChEMBL and ChEBI entries listed in the links table below, while the two enantiomers forming the racemate are represented by PubChem CID 3044368 and PubChem CID 3044369. The marketed formulations contain primaquine phosphate (PubChem CID 6135). The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
| 配体家族 | Antimalarial ligands |
| 1. Hill DR, Baird JK, Parise ME, Lewis LS, Ryan ET, Magill AJ. (2006) Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I.. Am J Trop Med Hyg, 75 (3): (402-15). [PMID:16968913] |
| 2. Thriemer K, Ley B, Bobogare A, Dysoley L, Alam MS, Pasaribu AP, Sattabongkot J, Jambert E, Domingo GJ, Commons R et al.. (2017) Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group.. Malar J, 16 (1): (141). [PMID:28381261] |
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