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甲氧氯普胺

规格或纯度: 98%

CAS编号: 364-62-5
分子式: C₁₄H₂₂ClN₃O₂
分子量: 299.8
Beilstein号: 1884366
EC号: 206-662-9
MDL号: MFCD00211338
PubChem编号: 4168

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货号 (SKU)	包装规格	是否现货	价格	数量
M124438-5g	5g	现货
M124438-25g	25g	现货
M124438-100g	100g	期货

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基本描述

规格或纯度	98%
英文名称	Metoclopramide
别名	4-氨基-5-氯-N-[2-(二乙氨基)乙基]-2-甲氧基苯甲酰胺
英文别名	4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide Methoxychloroprocainamide
生化机理	Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drμg of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drμg is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.
储存温度	2-8°C储存
运输条件	冰袋运输
产品介绍	Metoclopramide is a drug, which can be effective in the treatment of severe nausea and vomiting caused by the anticancer drug cis-platinum. Metoclopramide may be used as an analytical reference standard for the determination of the analyte in: · Human plasma by liquid-liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection. Metoclopramide is a drug, which can be effective in the treatment of severe nausea and vomiting caused by the anticancer drug cis-platinum. Metoclopramide may be used as an analytical reference standard for the determination of the analyte in: · Human plasma by liquid-liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection.

名称和标识符

EC号	206-662-9
IUPAC Name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
INCHI	InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
InChi Key	TTWJBBZEZQICBI-UHFFFAOYSA-N
Canonical SMILES	CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl
分子式	C₁₄H₂₂ClN₃O₂
PubChem CID	4168
Beilstein号	1884366
分子量	299.8

化学和物理性质

溶解性	Soluble in water (miscible), and ethanol.
敏感性	对热敏感
熔点	149°C

安全信息

象形图	Health Hazard Harmful
信号词	Danger
危险声明	H302: Harmful if swallowed H370: Causes damage to organs H362: May cause harm to breast-fed children
预防措施声明	P321,P405,P501,P264,P260,P270,P330,P263,P203,P301+P317,P318,P308+P316
WGK Germany	3
RTECS	BZ3300000

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