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聚乙二醇甲醚

规格或纯度: 平均分子量550
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货号 (SKU) 包装规格 是否现货 价格 数量
M109715-25g 25g 现货 Stock Image
M109715-100g 100g 现货 Stock Image
M109715-250g 250g 现货 Stock Image
M109715-500g 500g 现货 Stock Image
M109715-2.5kg 2.5kg 现货 Stock Image
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PEG化试剂 聚合物/高分子试剂
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基本描述

规格或纯度 平均分子量550
英文名称 Methoxypolyethylene glycol
别名 mPEG;甲氧基聚乙二醇
英文别名 Polyethylene glycol monomethylether; Poly(ethylene glycol) methyl ether
运输条件 常规运输

名称和标识符

EC号 215-801-2
分子式

CH3O(CH2CH2O)nH
PubChem CID 8019

化学和物理性质

密度 1.089
熔点 12°C
折光率 1.46
闪点(℃) 268°C

安全信息

WGK Germany 1
RTECS TR1581750

参考文献

1. Zhi-Xia Zhao,Shan-Yun Gao,Jian-Cheng Wang,Cheng-Jun Chen,En-Yu Zhao,Wen-Jie Hou,Qiang Feng,Ling-Yan Gao,Xiao-Yan Liu,Liang-Ren Zhang,Qiang Zhang.  (2012-06-23)  Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine(R15) triblock copolymer for siRNA delivery..  Biomaterials,  33  ((28)):  (6793-6807).  [PMID:22721724]
2. Smita K Pawar,Archana J Badhwar,Firuza Kharas,Jayant J Khandare,Pradeep R Vavia.  (2012-06-23)  Design, synthesis and evaluation of N-acetyl glucosamine (NAG)-PEG-doxorubicin targeted conjugates for anticancer delivery..  International journal of pharmaceutics,  436  ((1-2)):  (183-193).  [PMID:22721850]
3. Ke Wang,Wei Feng Li,Jian Feng Xing,Kai Dong,Yang Gao.  (2012-08-14)  Preliminary assessment of the safety evaluation of novel pH-sensitive hydrogel..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,  82  ((2)):  (332-339).  [PMID:22885157]
4. Junming Li,Zhiyao He,Shui Yu,Shuangzhi Li,Qing Ma,Yiyi Yu,Jialin Zhang,Rui Li,Yu Zheng,Gu He,Xiangrong Song.  (2012-08-15)  Micelles based on methoxy poly(ethylene glycol)-cholesterol conjugate for controlled and targeted drug delivery of a poorly water soluble drug..  Journal of biomedical nanotechnology,  8  ((5)):  (809-817).  [PMID:22888752]
5. Jiani Zheng,Hongguo Xie,Weiting Yu,Mingqian Tan,Faquan Gong,Xiudong Liu,Feng Wang,Guojun Lv,Wanfa Liu,Guoshuang Zheng,Yan Yang,Weiyang Xie,Xiaojun Ma.  (2012-08-28)  Enhancement of surface graft density of MPEG on alginate/chitosan hydrogel microcapsules for protein repellency..  Langmuir : the ACS journal of surfaces and colloids,  28  ((37)):  (13261-13273).  [PMID:22921144]
6. Yi Wei,Yu Xia Wang,Wei Wang,Sa V Ho,Feng Qi,Guang Hui Ma,Zhi Guo Su.  (2012-09-04)  Microcosmic mechanisms for protein incomplete release and stability of various amphiphilic mPEG-PLA microspheres..  Langmuir : the ACS journal of surfaces and colloids,  28  ((39)):  (13984-13992).  [PMID:22937802]
7. Robert K Delong,Azure Risor,Masaaki Kanomata,Amanda Laymon,Brooke Jones,Scott D Zimmerman,Joseph Williams,Colette Witkowski,Mathew Warner,Michael Ruff,Richard Garrad,John K Fallon,Anthony J Hickey,Reza Sedaghat-Herati.  (2012-09-05)  Characterization of biomolecular nanoconjugates by high-throughput delivery and spectroscopic difference..  Nanomedicine (London, England),  7  ((12)):  (1851-1862).  [PMID:22943129]
8. Na Li,Xin-Ru Li,Yan-Xia Zhou,Wen-Jing Li,Yong Zhao,Shu-Jin Ma,Jin-Wen Li,Ya-Jie Gao,Yan Liu,Xing-Lin Wang,Dong-Dong Yin.  (2012-09-15)  The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier..  Biomaterials,  33  ((34)):  (8881-8892).  [PMID:22975427]
9. Yanjie Bao,Yi Jin,Padmanabh Chivukula,Jun Zhang,Yun Liu,Jian Liu,Jean-Pierre Clamme,Ram I Mahato,Dominic Ng,Wenbin Ying,Yiting Wang,Lei Yu.  (2012-09-18)  Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes..  Pharmaceutical research,  30  ((2)):  (342-351).  [PMID:22983644]
10. Lina Du,Yiguang Jin,Jiangyong Yang,Shuangmiao Wang,Xiangtao Wang.  (2012-09-20)  A functionalized poly(amidoamine) nanocarrier-loading 5-fluorouracil: pH-responsive drug release and enhanced anticancer effect..  Anti-cancer drugs,  24  ((2)):  (172-180).  [PMID:22990130]
11. Junhwa Shin,Pochi Shum,Jessica Grey,Shin-ichi Fujiwara,Guarov S Malhotra,Andres González-Bonet,Seok-Hee Hyun,Elaine Moase,Theresa M Allen,David H Thompson.  (2012-10-04)  Acid-labile mPEG-vinyl ether-1,2-dioleylglycerol lipids with tunable pH sensitivity: synthesis and structural effects on hydrolysis rates, DOPE liposome release performance, and pharmacokinetics..  Molecular pharmaceutics,  9  ((11)):  (3266-3276).  [PMID:23030381]
12. Seung-Young Lee,Sungwon Kim,Jacqueline Y Tyler,Kinam Park,Ji-Xin Cheng.  (2012-10-20)  Blood-stable, tumor-adaptable disulfide bonded mPEG-(Cys)4-PDLLA micelles for chemotherapy..  Biomaterials,  34  ((2)):  (552-561).  [PMID:23079665]
13. Yunki Lee,Kyung Min Park,Jin Woo Bae,Ki Dong Park.  (2012-10-30)  Facile surface PEGylation via tyrosinase-catalyzed oxidative reaction for the preparation of non-fouling surfaces..  Colloids and surfaces. B, Biointerfaces,  102  ():  (585-589).  [PMID:23104029]
14. De-Hao Tsai,Melanie P Shelton,Frank W DelRio,Sherrie Elzey,Suvajyoti Guha,Michael R Zachariah,Vincent A Hackley.  (2012-10-30)  Quantifying dithiothreitol displacement of functional ligands from gold nanoparticles..  Analytical and bioanalytical chemistry,  404  ((10)):  (3015-3023).  [PMID:23104310]
15. Carsten Dingels,Sophie S Müller,Tobias Steinbach,Christine Tonhauser,Holger Frey.  (2012-12-22)  Universal concept for the implementation of a single cleavable unit at tunable position in functional poly(ethylene glycol)s..  Biomacromolecules,  14  ((2)):  (448-459).  [PMID:23256621]
16. Yiyi Yu,Yingju He,Bei Xu,Zhiyao He,Ying Zhang,Yan Chen,Yang Yang,Yongmei Xie,Yu Zheng,Gu He,Jun He,Xiangrong Song.  (2013-01-03)  Self-assembled methoxy poly(ethylene glycol)-cholesterol micelles for hydrophobic drug delivery..  Journal of pharmaceutical sciences,  102  ((3)):  (1054-1062).  [PMID:23280512]
17. Lei Liu,Lu Sun,Qinjie Wu,Wenhao Guo,Ling Li,YiShan Chen,Yuchen Li,Changyang Gong,Zhiyong Qian,Yuquan Wei.  (2013-01-05)  Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis..  International journal of pharmaceutics,  443  ((1-2)):  (175-182).  [PMID:23287774]
18. Mulu Z Tesfay,Amber C Kirk,Elizabeth M Hadac,Guy E Griesmann,Mark J Federspiel,Glen N Barber,Stephen M Henry,Kah-Whye Peng,Stephen J Russell.  (2013-01-18)  PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice..  Journal of virology,  87  ((7)):  (3752-3759).  [PMID:23325695]
19. Hyo Won Seo,Da Yeon Kim,Doo Yeon Kwon,Jin Seon Kwon,Ling Mei Jin,Bong Lee,Jae Ho Kim,Byoung Hyun Min,Moon Suk Kim.  (2013-01-25)  Injectable intratumoral hydrogel as 5-fluorouracil drug depot..  Biomaterials,  34  ((11)):  (2748-2757).  [PMID:23343635]
20. Dawei Yong,Yu Luo,Fang Du,Jin Huang,Wei Lu,Zhaoyun Dai,Jiahui Yu,Shiyuan Liu.  (2013-01-29)  CDDP supramolecular micelles fabricated from adamantine terminated mPEG and β-cyclodextrin based seven-armed poly (L-glutamic acid)/CDDP complexes..  Colloids and surfaces. B, Biointerfaces,  105  ():  (31-36).  [PMID:23352945]
21. Prakash G Avaji,Vithal B Jadhav,Jin Xin Cui,Yong Joo Jun,Hwa Jeong Lee,Youn Soo Sohn.  (2013-02-16)  Synthesis and physicochemical properties of new tripodal amphiphiles bearing fatty acids as a hydrophobic group..  Bioorganic & medicinal chemistry letters,  23  ((6)):  (1763-1767).  [PMID:23411081]
22. Shou-Cheng Wu,Kun-Liang Lin,Tzu-Pin Wang,Shey-Cherng Tzou,Gyan Singh,Ming-Hung Chen,Tian-Lu Cheng,Chiao-Yun Chen,Gin-Chung Liu,Te-Wei Lee,Shao-Hwa Hu,Yun-Ming Wang.  (2013-03-08)  Imaging specificity of MR-optical imaging agents following the masking of surface charge by poly(ethylene glycol)..  Biomaterials,  34  ((16)):  (4118-4127).  [PMID:23465830]
23. Rulin Cai,Rui Li,Jiasheng Qian,Anjian Xie,Kangming Nie.  (2013-03-19)  The morphology and fabrication of nanostructured micelle by a novel block copolymer with linear-dendritic structure..  Materials science & engineering. C, Materials for biological applications,  33  ((4)):  (2070-2077).  [PMID:23498234]
24. Zhifei Wang,Lin Jia,Min-Hui Li.  (2013-05-01)  Gold nanoparticles decorated by amphiphilic block copolymer as efficient system for drug delivery..  Journal of biomedical nanotechnology,  9  ((1)):  (61-68).  [PMID:23627068]
25. Zhe Xun,Xiaoyun Zhao,Yifu Guan.  (2013-08-09)  Improved thermal cycling durability and PCR compatibility of polymer coated quantum dot..  Nanotechnology,  24  ((35)):  (355504-355504).  [PMID:23924819]
26. Mark G P Saifer,L David Williams,Monika A Sobczyk,Shawnya J Michaels,Merry R Sherman.  (2013-11-10)  Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins..  Molecular immunology,  57  ((2)):  (236-246).  [PMID:24200843]
27. M Zouhair Atassi,Masooma Naqvi,Behzod Z Dolimbek,K Roger Aoki.  (2014-05-21)  Reduction of established antibody responses against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol peptide conjugates..  Journal of neuroimmunology,  272  ((1-2)):  (29-34).  [PMID:24841626]
28. George Mattheolabakis,Chi C Wong,Yu Sun,Carol A Amella,Robert Richards,Panayiotis P Constantinides,Basil Rigas.  (2014-07-23)  Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen..  The Journal of pharmacology and experimental therapeutics,  351  ((1)):  (61-66).  [PMID:25047517]
29. Sunanda Margrett Williams,Anu Vijayakumari Chandran,Sunita Prakash,Mamannamana Vijayan,Dipankar Chatterji.  (2017-08-22)  A Mutation Directs the Structural Switch of DNA Binding Proteins under Starvation to a Ferritin-like Protein Cage..  Structure (London, England : 1993),  25  ((9)):  (1449-1454).  [PMID:28823472]

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聚乙二醇修饰剂（PEG）的一般共轭反应——聚乙二醇胺（PEG-NH2）
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缓冲液 聚乙二醇修饰剂 聚乙二醇酸 聚乙二醇NHS活性酯 聚乙二醇胺
General Conjugation Protocols of PEG linkers——PEG Amine
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Buffer Polyethylene Glycol (PEG) PEG-COOH PEG-NHS Ester PEG-NH2
用于2D和3D细胞培养的可降解型聚乙二醇水凝胶
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture
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