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谷胱甘肽(还原型)

内源性抗氧化剂
规格或纯度: 98%
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货号 (SKU) 包装规格 是否现货 价格 数量
G105426-1g
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G105426-5g
5g 现货 Stock Image
G105426-10g
10g 现货 Stock Image
G105426-25g
25g 现货 Stock Image
G105426-50g
50g 现货 Stock Image
G105426-100g
100g 现货 Stock Image
G105426-250g
250g 现货 Stock Image
G105426-500g
500g 现货 Stock Image
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化学预防剂 多肽

基本描述

规格或纯度 98%
英文名称 Glutathione (Reduced)
别名 GSH|L-还原型谷胱甘肽(还原型)|L-谷胱甘肽|谷胱甘肽 还原型|谷胱甘肽还原型|5-L-谷氨酰-L-半胱氨酰甘氨酸还原型|谷胱甘肽还原型|还原谷胱甘肽还原型|硫糠质还原型|三缩氨基酸还原型|L -还原型谷胱甘肽
英文别名 glutathione|70-18-8|L-Glutathione|Glutathion|Isethion|L-Glutathione reduced|Tathion|Glutathione-SH|Glutinal|Tathione|reduced glutathione|Deltathione|Neuthion|Copren|Glutide|Triptide|Ledac|Glutatione|GSH|Glutatiol|Panaron|Glutathione SH|L-Glutatione|Glutat
生化机理 内源性抗氧化剂,对于减少在细胞代谢和呼吸中形成的活性氧发挥重要作用。谷胱甘肽-S-转移酶的催化与具有亲电中心的异源物(xenobiotics),白三烯,和其他分子形成谷胱甘肽硫醚。谷胱甘肽与蛋白质中的半胱氨酸残基形成二硫键。内源性抗氧化剂。清除羟基自由基,降低ROS。与蛋白质的半胱氨酸残基形成二硫键。防止毒性和疾病。乙二醛酶I的弱抑制剂(K i值= 18 mM)。
应用 做为体内一种重要的抗氧化剂,它能够清除掉人体内的自由基。解毒药,主要用于重金属、丙烯腈、氟化物、一氧化碳及有机溶剂等中毒。 可用5-10 mM从谷胱甘肽琼脂糖中洗脱谷胱甘肽-S-转移酶(GST)。
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
备注 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,这些产品最多可以使用一周。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。
产品介绍

用途:

做为体内一种重要的抗氧化剂的原料,它能够清除掉人体内的自由基。是解毒药的原料,主要用于重金属、丙烯腈、氟化物、一氧化碳及有机溶剂等中毒。可用5-10 mM从谷胱甘肽琼脂糖中洗脱谷胱甘肽-S-转移酶(GST)。

Amino Acid Sequence γ-Glu-Cys-Gly
May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

名称和标识符

EC号 200-725-4
IUPAC Name (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
INCHI InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChi Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Canonical SMILES C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N
WGK Germany 2
RTECS MC0556000
PubChem CID 124886
分子量 307.32
Beilstein号 1729812

化学和物理性质

溶解性 Soluble in DMF, ethanol, water (20 mg/ml) at 25 °C, PBS(pH7.2) (~10 mg/ml), diluted alcohol, liquid ammonia, and DMSO.
密度 1.441
敏感性 对空气敏感,对湿度敏感
比旋光度 -17 ° (C=2, H2O)
熔点 192-195°C

安全和危险性(GHS)

象形图
ghs08

Health Hazard

ghs05

Corrosive

ghs07

Harmful

信号词 Danger
危险声明 H315: Causes skin irritation
H335: May cause respiratory irritation
H341: Suspected of causing genetic defects
H318: Causes serious eye damage
预防措施声明 P261,P280,P302+P352,P321,P405,P501,P264,P281,P271,P304+P340,P403+P233,P362+P364,P203,P264+P265,P305+P354+P338,P318,P317,P332+P317,P319
WGK Germany 2
RTECS MC0556000
Merck Index 4475
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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