91高清自产国产拍,无码免费A级毛片大全,日本 欧美 国产中文字幕,99re热视频这里只有精品视频首页

首页   400-620-6333
提交您使用阿拉丁产品的研究文章，就得100元奖励！立即访问我们的提交页面.
语言
Chinese
切换导航
我的购物车
搜索
搜索444
高级搜索
菜单
账号
设置
语言
Chinese

D-谷氨酸

内源性非选择性激动剂。活性较低的对映体
规格或纯度: 98%
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
G100444-5g
 5g 现货 Stock Image
G100444-25g
 25g 现货 Stock Image
G100444-50g
 50g 现货 Stock Image
G100444-100g
 100g 现货 Stock Image
G100444-250g
 250g 现货 Stock Image
G100444-500g
 500g 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
不对称合成 肽化学
main product photo

基本描述

规格或纯度 98%
英文名称 D-Glutamic acid
别名 D-Glu|D-麸氨酸|(R)-2-氨基戊二酸|R-(-)-1-氨基丙烷-1,3-二羧酸
英文别名 D-glutamic acid|6893-26-1|(R)-2-aminopentanedioic acid|H-D-Glu-OH|(2R)-2-aminopentanedioic acid|D-Glu|D-glutamate|Glutamic acid D-form|D-2-Aminopentanedioic acid|D-Glutamicacid|D-(-)-Glutamic acid|R-(-)-Glutamic acid|D-Glutaminsaeure|D-Glutaminic acid|(r)
生化机理 作用于NMDA受体的兴奋性氨基酸；活性比L-异构体低。
应用 D-谷氨酸适用于GR酶（谷氨酸消旋酶）及其抑制剂的结构亲和关系（SAR）研究。
运输条件 常规运输
备注 1g、5g卖完停产，不再备货
产品介绍

谷氨酸的非天然异构体。水中溶解度:7 g/L (20°C)，实际上不溶于有机溶剂。D-谷氨酸适用于GR酶（谷氨酸消旋酶）及其抑制剂的结构亲和关系（SAR）研究。

D-谷氨酸是细菌肽聚糖结构的必需成分。可通过D-谷氨酸添加酶（murD）将其加入UDP-N-乙酰胞壁酰-L-丙氨酸（UDP-MurNAc-L-丙氨酸）中。然后将其掺入肽聚糖前体中。 肽聚糖构成革兰氏阳性和阴性细菌的细胞壁。通过谷氨酸消旋酶（GR）将L-谷氨酸转化为D-谷氨酸是肽聚糖合成中必不可少的步骤。

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.


application：

D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.

名称和标识符

EC号 230-000-8
IUPAC Name (2R)-2-aminopentanedioic acid
INCHI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChi Key WHUUTDBJXJRKMK-GSVOUGTGSA-N
Canonical SMILES C(CC(=O)O)C(C(=O)O)N
WGK Germany 1
PubChem CID 23327
分子量 147.13
Beilstein号 1723800
Reaxy-Rn 1723800

化学和物理性质

溶解性 溶于1eq. NaOH, 最高浓度 (mg/mL): None, 最高浓度(mM): 100
密度 1.409
比旋光度 -30.0 to -33.0 deg(C=5, HCl(1+5))
熔点 200-202°C

安全和危险性（GHS）

WGK Germany 1
Reaxy-Rn 1723800
Merck Index 4469
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

关联配体

Ligand ID 4708
名称 D-glutamic acid
别名 D-glutamate
类别 Metabolite
学名 (2R)-2-aminopentanedioic acid
生物活性评价 The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).
评价 Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth.

相关文档

质检报告COA

请输入批号:


 SDS中文版  SDS英文版

 质量技术规格说明书

产品问答

产品问答

登录提交问题 Hover me 请先登录再提交问题
查看全部
您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

参考文献

1. Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, Subramaniam S.  (2014)  Structural mechanism of glutamate receptor activation and desensitization..  Nature,  514  (7522):  (328-34).  [PMID:25119039]
2. P Doublet,J van Heijenoort,D Mengin-Lecreulx.  (1992-09-01)  Identification of the Escherichia coli murI gene, which is required for the biosynthesis of D-glutamic acid, a specific component of bacterial peptidoglycan..  Journal of bacteriology,  174  ((18)):  (5772-5779).  [PMID:1355768]
3. W Meyer,H M Poehling,K Neurand.  (1991-09-01)  Intraepidermal distribution of free amino acids in porcine skin..  Journal of dermatological science,  2  ((5)):  (383-392).  [PMID:1742249]
4. J H Cuervo,B Rodriguez,R A Houghten.  (1988-11-01)  The Magainins: sequence factors relevant to increased antimicrobial activity and decreased hemolytic activity..  Peptide research,  1  ((2)):  (81-86).  [PMID:2980783]
5. U Roll,J Scheeser,E Standl,A G Ziegler.  (1994-11-01)  Alterations of lymphocyte subsets in children of diabetic mothers..  Diabetologia,  37  ((11)):  (1132-1141).  [PMID:7867885]
6. Boudker O, Ryan RM, Yernool D, Shimamoto K, Gouaux E.  (2007)  Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter..  Nature,  445  (7126):  (387-93).  [PMID:17230192]
7. He S et al..  (2014)  Cholinergic modulation of large-conductance calcium-activated potassium channels regulates synaptic strength and spine calcium in cartwheel cells of the dorsal cochlear nucleus..  J Neurosci,  34  (15):  (5261-72).  [PMID:24719104]
8. Perez-Rosello T et al..  (2013)  Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis..  J Neurosci,  33  (22):  (9259-72).  [PMID:23719795]
9. Pierre Maechler,Asllan Gjinovci,Claes B Wollheim.  (2002-01-30)  Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas..  Diabetes,  51 Suppl 1  ():  (S99-102).  [PMID:11815466]
10. Sascha Dietrich,Jennifer Hüllein,Michael Hundemer,Nicola Lehners,Alexander Jethwa,David Capper,Till Acker,Boyan K Garvalov,Mindaugas Andrulis,Carolin Blume,Christoph Schulte,Thomas Mandel,Julia Meissner,Stefan Fr?hling,Christof von Kalle,Hanno Glimm,Anthony D Ho,Thorsten Zenz.  (2013-05-22)  Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology,  31  ((19)):  (e300-e303).  [PMID:23690412]
11. Sabine Ruehle,Floor Remmers,Hector Romo-Parra,Federico Massa,Melanie Wickert,Simone W?rtge,Martin H?ring,Nadine Kaiser,Giovanni Marsicano,Hans-Christian Pape,Beat Lutz.  (2013-06-21)  Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((25)):  (10264-10277).  [PMID:23785142]
12. P M Viral,C Nagarathna,B S Shakuntala.  (2013-07-17)  Chemomechanical caries removal in primary molars : evaluation of marginal leakage and shear bond strength in bonded restorations--an in vitro study..  The Journal of clinical pediatric dentistry,  37  ((3)):  (269-274).  [PMID:23855171]
13. Lu Qi,Qibin Qi,Sabrina Prudente,Christine Mendonca,Francesco Andreozzi,Natalia di Pietro,Mariella Sturma,Valeria Novelli,Gaia Chiara Mannino,Gloria Formoso,Ernest V Gervino,Thomas H Hauser,Jochen D Muehlschlegel,Monika A Niewczas,Andrzej S Krolewski,Gianni Biolo,Assunta Pandolfi,Eric Rimm,Giorgio Sesti,Vincenzo Trischitta,Frank Hu,Alessandro Doria.  (2013-08-29)  Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes..  JAMA,  310  ((8)):  (821-828).  [PMID:23982368]
14. E Yildiz,E Sirinkaraarslan,Z Yegin,M A Cebe,G Tosun.  (2013-12-04)  Effect of caries removal techniques on the bond strength of adhesives to caries-affected primary dentin in vitro..  European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry,  14  ((3)):  (209-214).  [PMID:24295006]
15. Ryan E Tooker,Mikhail Y Lipin,Valerie Leuranguer,Eva Rozsa,Jayne R Bramley,Jacqueline L Harding,Melissa M Reynolds,Jozsef Vigh.  (2013-12-07)  Nitric oxide mediates activity-dependent plasticity of retinal bipolar cell output via S-nitrosylation..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((49)):  (19176-19193).  [PMID:24305814]
16. Kohichi Tanaka.  (2013-12-18)  [Role of glutamate transporters in the pathophysiology of major mental illnesses]..  Nihon yakurigaku zasshi. Folia pharmacologica Japonica,  142  ((6)):  (291-296).  [PMID:24334928]
17. Qing Cheng,Jerrel L Yakel.  (2014-01-02)  Presynaptic α7 nicotinic acetylcholine receptors enhance hippocampal mossy fiber glutamatergic transmission via PKA activation..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((1)):  (124-133).  [PMID:24381273]
18. Kjell Heuser,Karolina Szokol,Erik Taub?ll.  (2014-01-17)  The role of glial cells in epilepsy..  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,  134  ((1)):  (37-41).  [PMID:24429754]
19. Nils Muhlert,Matteo Atzori,Enrico De Vita,David L Thomas,Rebecca S Samson,Claudia A M Wheeler-Kingshott,Jeroen J G Geurts,David H Miller,Alan J Thompson,Olga Ciccarelli.  (2014-01-17)  Memory in multiple sclerosis is linked to glutamate concentration in grey matter regions..  Journal of neurology, neurosurgery, and psychiatry,  85  ((8)):  (833-839).  [PMID:24431465]
20. Yumi Hayashi,Ryoji Tsurumizu,Jun Tsukahara,Kazuki Takeda,Shin-ichiro Narita,Makiko Mori,Kunio Miki,Hajime Tokuda.  (2014-02-27)  Roles of the protruding loop of factor B essential for the localization of lipoproteins (LolB) in the anchoring of bacterial triacylated proteins to the outer membrane..  The Journal of biological chemistry,  289  ((15)):  (10530-10539).  [PMID:24569999]
21. Minhajuddin Sirajuddin,Luke M Rice,Ronald D Vale.  (2014-03-19)  Regulation of microtubule motors by tubulin isotypes and post-translational modifications..  Nature cell biology,  16  ((4)):  (335-344).  [PMID:24633327]
22. Daiane Cattani,Vera Lúcia de Liz Oliveira Cavalli,Carla Elise Heinz Rieg,Juliana Tonietto Domingues,Tharine Dal-Cim,Carla Inês Tasca,Fátima Regina Mena Barreto Silva,Ariane Zamoner.  (2014-03-19)  Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity..  Toxicology,  320  ():  (34-45).  [PMID:24636977]
23. Elie Dolgin.  (2014-04-04)  Therapeutics: Negative feedback..  Nature,  508  ((7494)):  (S10-S11).  [PMID:24695327]
24. Mayumi Yamada,Yusuke Seto,Shinichiro Taya,Tomoo Owa,Yukiko U Inoue,Takayoshi Inoue,Yoshiya Kawaguchi,Yo-Ichi Nabeshima,Mikio Hoshino.  (2014-04-04)  Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((14)):  (4786-4800).  [PMID:24695699]
25. Raimund Helbok,Alois Schiefecker,Margarete Delazer,Ronny Beer,Thomas Bodner,Bettina Pfausler,Thomas Benke,Peter Lackner,Marlene Fischer,Florian Sohm,Werner Hackl,John F Stover,Claudius Thomé,Christian Humpel,Erich Schmutzhard.  (2014-04-18)  Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome..  Journal of neurology, neurosurgery, and psychiatry,  86  ((1)):  (79-86).  [PMID:24741064]
26. Joshua D Bell,Theresa Currier Thomas,Elliot Lass,Jinglu Ai,Hoyee Wan,Jonathan Lifshitz,Andrew J Baker,R Loch Macdonald.  (2014-04-22)  Platelet-mediated changes to neuronal glutamate receptor expression at sites of microthrombosis following experimental subarachnoid hemorrhage..  Journal of neurosurgery,  121  ((6)):  (1424-1431).  [PMID:24745710]
27. Yang-Kai Wang,Du Shen,Qiang Hao,Qiang Yu,Zhao-Tang Wu,Yu Deng,Yan-Fang Chen,Wen-Jun Yuan,Qi-Kuan Hu,Ding-Feng Su,Wei-Zhong Wang.  (2014-05-20)  Overexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats..  American journal of physiology. Heart and circulatory physiology,  307  ((2)):  (H182-H190).  [PMID:24838502]
28. Hiromi Yoshida,Akihide Yoshihara,Misa Teraoka,Yuji Terami,Goro Takata,Ken Izumori,Shigehiro Kamitori.  (2014-05-23)  X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate..  The FEBS journal,  281  ((14)):  (3150-3164).  [PMID:24846739]
29. Mette H Poulsen,Jacob Andersen,Rune Christensen,Kasper B Hansen,Stephen F Traynelis,Kristian Str?mgaard,Anders Skov Kristensen.  (2014-05-28)  Binding of ArgTX-636 in the NMDA receptor ion channel..  Journal of molecular biology,  427  ((1)):  (176-189).  [PMID:24862283]
30. Ali Alhoshani,Rosemarie Vithayathil,Jonathan Bandong,Katherine M Chrunyk,Gabriel O Moreno,Gregory A Weiss,Melanie J Cocco.  (2014-05-28)  Glutamate provides a key structural contact between reticulon-4 (Nogo-66) and phosphocholine..  Biochimica et biophysica acta,  1838  ((9)):  (2350-2356).  [PMID:24863057]
31. Jie Du,Xiao-Hui Li,Wang Zhang,Yong-Mei Yang,Yue-Han Wu,Wen-Qun Li,Jun Peng,Yuan-Jian Li.  (2014-05-29)  Involvement of glutamate-cystine/glutamate transporter system in aspirin-induced acute gastric mucosa injury..  Biochemical and biophysical research communications,  450  ((1)):  (135-141).  [PMID:24866234]
32. Flávio Afonso Gon?alves Mour?o,Hércules Ribeiro Leite,Luciana Estefani Drumond de Carvalho,Talita Hélen Ferreira E Vieira,Mauro Cunha Xavier Pinto,Daniel de Castro Medeiros,Ian Lara Lamounier Andrade,Daniela Fontes Gon?alves,Grace Schenatto Pereira,Márcio Flávio Dutra Moraes,André Ricardo Massensini.  (2014-06-07)  Neuroprotective effect of exercise in rat hippocampal slices submitted to in vitro ischemia is promoted by decrease of glutamate release and pro-apoptotic markers..  Journal of neurochemistry,  131  ((1)):  (65-73).  [PMID:24903976]
33. Wilson I Gonsalves,Michelle R Mahoney,Daniel J Sargent,Garth D Nelson,Steven R Alberts,Frank A Sinicrope,Richard M Goldberg,Paul J Limburg,Stephen N Thibodeau,Axel Grothey,Joleen M Hubbard,Emily Chan,Suresh Nair,Jeffrey L Berenberg,Robert R McWilliams.  (2014-06-14)  Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147..  Journal of the National Cancer Institute,  106  ((7)):  (doi:10-doi:10).  [PMID:24925349]
34. Hongying Wei,Furong Deng,Yiyong Chen,Yu Qin,Yu Hao,Xinbiao Guo.  (2014-06-17)  Ultrafine carbon black induces glutamate and ATP release by activating connexin and pannexin hemichannels in cultured astrocytes..  Toxicology,  323  ():  (32-41).  [PMID:24932759]
35. Helen N Saada,Ussama Z Said,Elsayed M E Mahdy,Hattem E Elmezayen,Shereen M Shedid.  (2014-06-18)  Fish oil omega-3 fatty acids reduce the severity of radiation-induced oxidative stress in the rat brain..  International journal of radiation biology,  90  ((12)):  (1179-1183).  [PMID:24937371]
36. Hirotoshi Morishita,Daisuke Kurita,Kunishige Kataoka,Takeshi Sakurai.  (2014-06-22)  Study on dioxygen reduction by mutational modifications of the hydrogen bond network leading from bulk water to the trinuclear copper center in bilirubin oxidase..  Biochemical and biophysical research communications,  450  ((1)):  (767-772).  [PMID:24952160]
37. Jill Harned,Steven Nagar,M Christine McGahan.  (2014-06-28)  Hypoxia controls iron metabolism and glutamate secretion in retinal pigmented epithelial cells..  Biochimica et biophysica acta,  1840  ((10)):  (3138-3144).  [PMID:24972165]
38. Isaac Marin-Valencia,M Ali Hooshyar,Kumar Pichumani,A Dean Sherry,Craig R Malloy.  (2014-09-19)  The ratio of acetate-to-glucose oxidation in astrocytes from a single 13C NMR spectrum of cerebral cortex..  Journal of neurochemistry,  132  ((1)):  (99-109).  [PMID:25231025]
39. Margarita V Glazova,Liubov S Nikitina,Kirill A Hudik,Olga D Kirillova,Nadezhda A Dorofeeva,Anatoly A Korotkov,Elena V Chernigovskaya.  (2014-10-30)  Inhibition of ERK1/2 signaling prevents epileptiform behavior in rats prone to audiogenic seizures..  Journal of neurochemistry,  132  ((2)):  (218-229).  [PMID:25351927]
40. Daniel R Dempsey,Kristen A Jeffries,Jason D Bond,Anne-Marie Carpenter,Santiago Rodriguez-Ospina,Leonid Breydo,K Kenneth Caswell,David J Merkler.  (2014-11-19)  Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases..  Biochemistry,  53  ((49)):  (7777-7793).  [PMID:25406072]
41. Frederic J Kaye,Alison M Ivey,Walter E Drane,William M Mendenhall,Robert W Allan.  (2014-12-06)  Clinical and radiographic response with combined BRAF-targeted therapy in stage 4 ameloblastoma..  Journal of the National Cancer Institute,  107  ((1)):  (378-378).  [PMID:25475564]
42. Wangfa Zhao,Shih-Chieh Chuang,Steven R Young,Riccardo Bianchi,Robert K S Wong.  (2015-01-09)  Extracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampus..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  35  ((1)):  (308-315).  [PMID:25568123]
43. Yasuo Watanabe,Kohki Kawata,Seiya Watanabe.  (2015-04-29)  Monitoring Technology for Gamma-Aminobutyric acid Production in Polished Mochi Barley Grains using a Carbon Dioxide Sensor..  Journal of food science,  80  ((6)):  (H1418-H1424).  [PMID:25916326]
44. Zhe Yang,Rui Huang,Xin Fu,Gaohang Wang,Wei Qi,Decai Mao,Zhaomei Shi,Wei L Shen,Liming Wang.  (2018-09-14)  A post-ingestive amino acid sensor promotes food consumption in Drosophila..  Cell research,  28  ((10)):  (1013-1025).  [PMID:30209352]
45. S M Majid,A S Liss,M You,H R Bose.  (2005-09-28)  The suppression of SH3BGRL is important for v-Rel-mediated transformation..  Oncogene,  25  ((5)):  (756-768).  [PMID:16186799]
46. Matthew Volgraf,Pau Gorostiza,Rika Numano,Richard H Kramer,Ehud Y Isacoff,Dirk Trauner.  (2006-01-13)  Allosteric control of an ionotropic glutamate receptor with an optical switch..  Nature chemical biology,  2  ((1)):  (47-52).  [PMID:16408092]
47. Stéphane P Ha?s,Jorge M Ordonez,Douglas G Burrin,Agneta L Sunehag.  (2007-07-12)  Dietary glutamate is almost entirely removed in its first pass through the splanchnic bed in premature infants..  Pediatric research,  62  ((3)):  (353-356).  [PMID:17622957]
48. Yohei Okubo.  (2013-06-06)  [Imaging non-synaptic transmission via glutamate]..  Brain and nerve = Shinkei kenkyu no shinpo,  65  ((6)):  (651-658).  [PMID:23735527]
49. Tomoyuki Mashimo,Kumar Pichumani,Vamsidhara Vemireddy,Kimmo J Hatanpaa,Dinesh Kumar Singh,Shyam Sirasanagandla,Suraj Nannepaga,Sara G Piccirillo,Zoltan Kovacs,Chan Foong,Zhiguang Huang,Samuel Barnett,Bruce E Mickey,Ralph J DeBerardinis,Benjamin P Tu,Elizabeth A Maher,Robert M Bachoo.  (2014-12-20)  Acetate is a bioenergetic substrate for human glioblastoma and brain metastases..  Cell,  159  ((7)):  (1603-1614).  [PMID:25525878]
上海阿拉丁生化科技股份有限公司
销售条款及条件 ? ? ? ? 隐私政策
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
沪公网安备 31012002004058号 沪ICP备09093490号-2

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。

上海工商 危险品化学品经营许可证（带存储）营业执照(三证合一)

91高清自产国产拍,无码免费A级毛片大全,日本 欧美 国产中文字幕,99re热视频这里只有精品视频首页

品牌简介

{转码主词}