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FITC-CM-葡聚糖
一种阴离子荧光葡聚糖，可用于研究细胞过程
规格或纯度:
150 kDa
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基本描述
| 规格或纯度 | 150 kDa |
|---|---|
| 英文名称 | FITC-CM-Dextran |
| 别名 | FITC-CM-葡聚糖 150, 异硫氰酸荧光素-羧甲基-右旋糖酐 |
| 英文别名 | TRITC-Dextran 20 TRITC-Dextran |
| 储存温度 | 2-8°C储存,避光,充氩,干燥 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
FITC-CM-dextrans are standard FITC-dextran carrying carboxymethyl-substituents. FITC-CM-dextrans have been developed for special studies on membranes and cells. The CM (carboxymethyl) group gives the product anionic (negative) charge. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-CM-dextrans from 4 kDa to 150 kDa. FITC-CM-dextran is supplied as a yellow powder. Structure FITC-CM-dextrans are manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali whereby O-carboxymethyl groups are introduced along the dextran chain. The carboxyl content is approximately 5% which is equivalent to about one CM group for every five glucose units. Thereafter, fluorescein (FITC) groups are introduced by reaction with fluorescein isothiocyanate. The degree of substitution of FITC lies between 0.003 – 0.008. Application FITC-CM-dextran are mostly used for studies of permeability and microcirculation. The carboxyl groups will impart an overall negative charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues. The free carboxyl group is also useful for coupling other substances to the dextran chain. FITC-CM-dextrans are standard FITC-dextran carrying carboxymethyl-substituents. FITC-CM-dextrans have been developed for special studies on membranes and cells. The CM (carboxymethyl) group gives the product anionic (negative) charge. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-CM-dextrans from 4 kDa to 150 kDa. FITC-CM-dextran is supplied as a yellow powder. Structure FITC-CM-dextrans are manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali whereby O-carboxymethyl groups are introduced along the dextran chain. The carboxyl content is approximately 5% which is equivalent to about one CM group for every five glucose units. Thereafter, fluorescein (FITC) groups are introduced by reaction with fluorescein isothiocyanate. The degree of substitution of FITC lies between 0.003 – 0.008. Application FITC-CM-dextran are mostly used for studies of permeability and microcirculation. The carboxyl groups will impart an overall negative charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues. The free carboxyl group is also useful for coupling other substances to the dextran chain. |
化学和物理性质
| 溶解性 | 易溶于水。 |
|---|---|
| 敏感性 | 对光和空气、湿度敏感 |
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