| 规格或纯度 | 10mM in DMSO |
|---|---|
| 英文名称 | 2′-Deoxyuridine 5′-mono-phos-phate disodium salt |
| 别名 | dUMP |
| 英文别名 | dUMP;2'-dUMP;2'-Deoxyuridine-5'-monophosphoric acid disodium salt |
| 生化机理 | 胸苷酸合成酶（TS）（EC 2.1.1.45）用于从头生产dTMP。dUMP类似物在潜在化疗应用中的研究中的参考底物。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
2′-Deoxyuridine 5′-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications. 2′-Deoxyuridine 5′-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications. |
| EC号 | 255-687-1 |
|---|---|
| IUPAC Name | disodium;[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl phosphate |
| INCHI | InChI=1S/C9H13N2O8P.2Na/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1 |
| InChi Key | FXVXMLXAXVVONE-CDNBRZBRSA-L |
| Canonical SMILES | C1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)([O-])[O-])O.[Na+].[Na+] |
| 分子式 |
C9H11N2Na2O8P |
| PubChem CID | 13957223 |
| 分子量 | 352.15 |
| 象形图 |
Harmful |
|---|---|
| 信号词 | Warning |
| 危险声明 |
H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed |
| 预防措施声明 | P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319 |
| WGK Germany | 3 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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