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1,4-二硫苏糖醇

还原剂

规格或纯度: ≥97%

CAS编号: 3483-12-3
分子式: C₄H₁₀O₂S₂
分子量: 154.25
Beilstein号: 1719760
EC号: MFCD00004877
MDL号: MFCD00004877
PubChem编号: 446094

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货号 (SKU)	包装规格	是否现货	价格	数量
D265376-1g	1g	现货
D265376-5g	5g	现货
D265376-25g	25g	现货
D265376-100g	100g	现货

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聚合物/高分子试剂蛋白质组学还原反应

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基本描述

规格或纯度	≥97%
英文名称	1,4-Dithiothreitol (DTT)
别名	1,4-二巯基苏糖醇, 克莱兰氏试剂\|DL-1,4-二硫苏糖醇\|二硫代苏糖醇\|DL-二硫苏糖醇
英文别名	Dithiothreitol\|DL-1,4-Dithiothreitol\|dl-Dithiothreitol\|3483-12-3\|(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL\|1,4-Dithiothreitol\|D-1,4-Dithiothreitol\|D-Dithiothreitol\|27565-41-9\|D-Dtt\|1,4-Dithio-dl-threitol\|threo-1,4-Dimercapto-2,3-butanediol\|(2S,3S)-1,4-disulfa
储存温度	2-8°C储存,避光,充氩
运输条件	冰袋运输
产品介绍	Overview Reducing agent Application Use 1,4-Dithiothreitol primarily to protect free SH-groups from oxidation. Use it routinely in all work with enzymes and proteins during enzyme measurement and the characterization of proteins. ? As one of the reduction and alkylation reactants of the main allergen αs1-casein in milk. ? As a component of sperm membrane removal and reactivation medium. ?Because mercaptans can effectively protect the active sites of biocatalysts and maintain the stability of enzymes. ? As a reducing agent to test the substitution of N-alkaline maleic substitution and the reaction of excess radicals. Before SDS-PAGE, DTT can effectively reduce protein disulfide bonds in the sample buffer. Both the irritation and toxicity of DTT are reduced by 2-mercaptoethanol. Usually, the required concentration of DTT (100mM) is used. It uses one-seventh of the concentration of 2-cholesterol-based ethanol (5% v/v, 700 mM). Benefits 1.Rely on the higher stability of DTT in comparison to 2-mercaptoethanol in aqueous solution 2.Experience more convenience and a less disagreeable odor 3.Benefit from the reduced tendency to oxidize in air. Specification Appearance: White to yellowish crystallizate DTT (with Ellman's reagent): ≥97% Thin layer chromatography: Chromatographically homogeneous, corresponds to reference Stability: At +2 to +8°C within specification range for 24 months. Store dry. Protect from light. Overview Reducing agent Application Use 1,4-Dithiothreitol primarily to protect free SH-groups from oxidation. Use it routinely in all work with enzymes and proteins during enzyme measurement and the characterization of proteins. ? As one of the reduction and alkylation reactants of the main allergen αs1-casein in milk. ? As a component of sperm membrane removal and reactivation medium. ?Because mercaptans can effectively protect the active sites of biocatalysts and maintain the stability of enzymes. ? As a reducing agent to test the substitution of N-alkaline maleic substitution and the reaction of excess radicals. Before SDS-PAGE, DTT can effectively reduce protein disulfide bonds in the sample buffer. Both the irritation and toxicity of DTT are reduced by 2-mercaptoethanol. Usually, the required concentration of DTT (100mM) is used. It uses one-seventh of the concentration of 2-cholesterol-based ethanol (5% v/v, 700 mM). Benefits 1.Rely on the higher stability of DTT in comparison to 2-mercaptoethanol in aqueous solution 2.Experience more convenience and a less disagreeable odor 3.Benefit from the reduced tendency to oxidize in air. Specification Appearance: White to yellowish crystallizate DTT (with Ellman's reagent): ≥97% Thin layer chromatography: Chromatographically homogeneous, corresponds to reference Stability: At +2 to +8°C within specification range for 24 months. Store dry. Protect from light.

名称和标识符

EC号	MFCD00004877
IUPAC Name	(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol
INCHI	InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChi Key	VHJLVAABSRFDPM-QWWZWVQMSA-N
Canonical SMILES	C(C(C(CS)O)O)S
WGK Germany	3
RTECS	EK1610000
关联CAS	27565-41-9
PubChem CID	446094
分子量	154.25
Beilstein号	1719760
Reaxy-Rn	1719757

化学和物理性质

溶解性	Soluble in water, ethanol, chloroform, diethyl ether, acetone, ether and ethyl acetate
密度	1.302
敏感性	空气及热和湿度敏感
闪点(℉)	235.4 °F
闪点(℃)	113 °C
沸点	125～130°C
熔点	42-43°C

安全和危险性（GHS）

象形图	Corrosive Harmful
信号词	Danger
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed H318: Causes serious eye damage
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P305+P354+P338,P317,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	EK1610000
Reaxy-Rn	1719757
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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