| 规格或纯度 | ≥99% |
|---|---|
| 英文名称 | 3-(Benzyldimethylammonio)propanesulfonate |
| 别名 | NDSB 256;PDA |
| 英文别名 | 3-(N-Phenylmethyl-N,N-dimethylammonio)propanesulfonate; 3-[Benzyl(dimethyl)ammonio]propane-1-sulphonate; NDSB 256; PDA |
| 生化机理 | 两性离子非洗涤剂磺基甜菜碱。用于提取，溶解和结晶蛋白质。防止蛋白质聚集并促进变性蛋白质的复性。 |
| 应用 | A nondetergent sulfobetaines class member. |
| 运输条件 | 常规运输 |
| 备注 | 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| 产品介绍 |
NDSB-256 is a nondetergent sulfobetaines class member. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb near UV range significantly. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. At 1 M, NDSB-256 will restore 30% of the enzymatic activity of denatured egg white lysozyme; at 800 mM it will restore 16% of the enzymatic activity of denatured β-galactosidase.A nondetergent sulfobetaines class member. NDSB-256 is a nondetergent sulfobetaines class member. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb near UV range significantly. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. At 1 M, NDSB-256 will restore 30% of the enzymatic activity of denatured egg white lysozyme; at 800 mM it will restore 16% of the enzymatic activity of denatured β-galactosidase. |
| IUPAC Name | 3-[benzyl(dimethyl)azaniumyl]propane-1-sulfonate |
|---|---|
| INCHI | InChI=1S/C12H19NO3S/c1-13(2,9-6-10-17(14,15)16)11-12-7-4-3-5-8-12/h3-5,7-8H,6,9-11H2,1-2H3 |
| InChi Key | MEJASPJNLSQOAG-UHFFFAOYSA-N |
| Canonical SMILES | C[N+](C)(CCCS(=O)(=O)[O-])CC1=CC=CC=C1 |
| WGK Germany | 3 |
| PubChem CID | 4386830 |
| 分子量 | 257.35 |
| Beilstein号 | 9194882 |
| WGK Germany | 3 |
|---|---|
| 个人防护装备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
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